所有图片(1)
About This Item
线性分子式:
(CH3)3N(Cl)CH2CH2OH
CAS号:
分子量:
139.62
Beilstein:
3563126
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
pharmaceutical primary standard
制造商/商品名称
USP
mp
302-305 °C (dec.) (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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相关类别
一般描述
本产品按照发行药典的发行和规定提供。支持本产品的所有信息，包括安全数据表和任何产品信息传单，都是在发行药典的授权下开发和发布的。如需进一步信息和支持，请访问现行药典网站。
应用
- 生物活性化合物的提取：氯化胆碱与蔗糖组成的天然深共晶溶剂有助于形成双水相系统。这些系统应用于药物提取过程可提高效率和选择性，特别是在制药应用中（Ghaffari et al., 2024）。
- α-葡萄糖苷酶抑制剂的提取：利用氯化胆碱基深共晶溶剂显著提高了从废种子中选择性提取α-葡萄糖苷酶抑制剂的效率。该应用在糖尿病治疗药物的开发中特别价值，展示了其在药物提取过程中的多功能性（Liu et al., 2024）。
底物
胆碱乙酰基转移酶底物
分析说明
这些产品仅供测试和化验使用。它们不适用于人类或动物，也不能用于诊断、治疗或治愈任何类型的疾病。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Xinyin Jiang et al.
Journal of cellular physiology, 229(8), 1016-1027 (2014-03-22)
Maternal choline intake during gestation may influence placental function and fetal health outcomes. Specifically, we previously showed that supplemental choline reduced placental and maternal circulating concentrations of the anti-angiogenic factor, fms-like tyrosine kinase-1 (sFLT1), in pregnant women as well as
Zhuo Li et al.
Biochimica et biophysica acta, 1840(7), 2112-2122 (2014-03-19)
Choline kinase has three isoforms encoded by the genes Chka and Chkb. Inactivation of Chka in mice results in embryonic lethality, whereas Chkb(-/-) mice display neonatal forelimb bone deformations. To understand the mechanisms underlying the bone deformations, we compared the
Francina Agosti et al.
The European journal of neuroscience, 40(5), 2755-2765 (2014-06-20)
The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor involved in food intake and energy expenditure regulation. MC4R activation modifies neuronal activity but the molecular mechanisms by which this regulation occurs remain unclear. Here, we tested the hypothesis that
O Hemminki et al.
International journal of cancer, 134(12), 2878-2890 (2013-11-20)
At present, it is not possible to reliably identify patients who will benefit from oncolytic virus treatments. Conventional modalities such as computed tomography (CT), which measure tumor size, are unreliable owing to inflammation-induced tumor swelling. We hypothesized that magnetic resonance
Brook T Chernet et al.
Oncotarget, 5(10), 3287-3306 (2014-05-17)
The microenvironment is increasingly recognized as a crucial aspect of cancer. In contrast and complement to the field's focus on biochemical factors and extracellular matrix, we characterize a novel aspect of host:tumor interaction - endogenous bioelectric signals among non-excitable somatic
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