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Merck
CN

1118328

USP

4,7-二氯喹啉

United States Pharmacopeia (USP) Reference Standard

别名:

4,7-Dichloroquinoline

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关于此项目

经验公式（希尔记法）:
C9H5Cl2N
化学文摘社编号:
86-98-6
分子量:
198.05
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749321
MDL number:
MFCD00006774
Beilstein/REAXYS Number:
125359

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产品名称

4,7-二氯喹啉, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H

SMILES string

Clc1ccc2c(Cl)ccnc2c1

InChI key

HXEWMTXDBOQQKO-UHFFFAOYSA-N

biological source

synthetic

grade

pharmaceutical primary standard

agency

USP

vapor pressure

0.0000811 kPa ( 25 °C)

API family

chloroquine

form

crystalline

packaging

pkg of 15 mg
pkg of 25 mg

manufacturer/tradename

USP

color

off-white to brown-yellowish

bp

298.4 °F (148°C)

mp

81-83 °C (lit.)

solubility

ethanol: freely soluble
ether: freely soluble
water: slightly soluble

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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相关类别

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Chloroquine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Chloroquine Phosphate

General description

Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chloroquine Phosphate USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 959-959 (2020)
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)

实验方案

Chloroquine Phosphate HPLC Assay & Impurity Profiling

Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

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