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Merck
CN

1096724

USP

卡莫司汀

United States Pharmacopeia (USP) Reference Standard

别名:

1,3-双(2-氯乙基)-1-亚硝基脲, BCNU

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About This Item

经验公式(希尔记法):
C5H9Cl2N3O2
CAS号:
分子量:
214.05
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

carmustine

形式

(Oily liquid to amorphous solid)

制造商/商品名称

USP

mp

30 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

−20°C

SMILES字符串

ClCCNC(=O)N(CCCl)N=O

InChI

1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

InChI key

DLGOEMSEDOSKAD-UHFFFAOYSA-N

基因信息

human ... GSR(2936)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用


  • Enhancing glioblastoma treatment: Overexpression of Let-7a-3p in U87MG glioblastoma cells enhances chemosensitivity to Carmustine, promoting autophagy and suppressing cell survival, suggesting its role in improving outcomes in glioblastoma multiforme treatment using antineoplastic alkylating compounds (Bahojb Mahdavi et al., 2024).

  • Pharmacogenomic profiling in renal cancer: Characterization of mitoribosomal small subunit genes in renal cell carcinoma reveals significant implications for Carmustine′s pharmacogenomic interaction, enhancing understanding of its mechanism in cancer therapy and providing a basis for personalized treatment approaches (Wei et al., 2024).

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral - Carc. 1B - Repr. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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