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Merck
CN

1075757

USP

比索洛尔 半富马酸盐

United States Pharmacopeia (USP) Reference Standard

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别名:
1- [4-[[2-(1-甲基乙氧基)乙氧基]甲基]苯氧基] -3-[(1-甲基乙基)氨基] -2-丙醇 半富马酸盐
经验公式(希尔记法):
C18H31NO4 · .5C4H4O4
分子量:
383.48
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

bisoprolol

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2

InChI

1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key

VMDFASMUILANOL-WXXKFALUSA-N

基因信息

human ... ADRB1(153)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用


  • Chromatographic Techniques for Assessment of Bisoprolol Fumarate and Perindopril Arginine in Solid Formulations under Various Stress Conditions and Application to Six Sigma, Content Uniformity, and Comparative Dissolution Approaches - Presents advanced chromatographic methods to assess Bisoprolol fumarate in pharmaceutical formulations, crucial for ensuring high standards in drug quality and stability (Mahmoud OA et al., 2023).

生化/生理作用

心脏选择性 β1-肾上腺素受体拮抗剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 2 - STOT RE 2

靶器官

Heart

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Bisoprolol Fumarate Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(5) (2013)
Bisoprolol Fumarate and Hydrochlorothiazide Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(2) (2013)
Naseem A Charoo et al.
Journal of pharmaceutical sciences, 103(2), 378-391 (2014-01-03)
Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing bisoprolol as the sole active pharmaceutical ingredient (API) are reviewed. Bisoprolol is classified
Does β selectivity really affect outcome?
Jordan Field Wicker et al.
Anesthesiology, 120(5), 1286-1287 (2014-04-24)
In reply.
Catherine Ashes et al.
Anesthesiology, 120(5), 1287-1288 (2014-04-24)

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