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Merck
CN

1065210

USP

盐酸小檗碱

United States Pharmacopeia (USP) Reference Standard

别名:

小檗碱 CRM 氯化物形式, 黄连素

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关于此项目

经验公式（希尔记法）:
C20H18ClNO4
化学文摘社编号:
633-65-8
分子量:
371.81
PubChem Substance ID:
329748923
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00011939
Colour Index Number:
75160
Beilstein/REAXYS Number:
3836585

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产品名称

盐酸小檗碱, United States Pharmacopeia (USP) Reference Standard

SMILES string

COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

grade

pharmaceutical primary standard

API family

berberine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Application

肥大细胞中肝素的荧光染色
Berberine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Coptis Species Rhizome
  • Coptis Species Rhizome Dry Extract
  • Coptis Species Rhizome Powder
  • Goldenseal
  • Indian Barberry Stem
  • Indian Barberry Stem Dry Extract
  • Indian Barberry Stem Powder

Biochem/physiol Actions

一种抗生素特性较弱的生物碱。MDR外排泵的底物。小檗碱的抗微生物活性可通过MDR抑制剂5'-甲氧基氢化物（5'-MHC）加强。小檗碱可上调肝癌细胞中Pgp的表达。用小檗碱进行治疗可能会减少化学治疗药物的积累。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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