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Merck
CN

1065210

USP

盐酸小檗碱

United States Pharmacopeia (USP) Reference Standard

别名:

小檗碱 CRM 氯化物形式, 黄连素

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About This Item

经验公式(希尔记法):
C20H18ClNO4
CAS号:
分子量:
371.81
颜色索引号:
75160
Beilstein:
3836585
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

berberine

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Berberine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Coptis Species Rhizome
  • Coptis Species Rhizome Dry Extract
  • Coptis Species Rhizome Powder
  • Goldenseal
  • Indian Barberry Stem
  • Indian Barberry Stem Dry Extract
  • Indian Barberry Stem Powder
肥大细胞中肝素的荧光染色

生化/生理作用

一种抗生素特性较弱的生物碱。MDR外排泵的底物。小檗碱的抗微生物活性可通过MDR抑制剂5'-甲氧基氢化物(5'-MHC)加强。小檗碱可上调肝癌细胞中Pgp的表达。用小檗碱进行治疗可能会减少化学治疗药物的积累。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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