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关于此项目
经验公式（希尔记法）:
C66H68CaF2N4O10 · 3H2O
化学文摘社编号:
分子量:
1209.39
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
SMILES string
[Ca+2].Fc5ccc(cc5)c6[n](c(c(c6c8ccccc8)C(=O)Nc7ccccc7)C(C)C)CC[C@@H](O)C[C@@H](O)CC(=O)O.Fc1ccc(cc1)c2[n](c(c(c2c4ccccc4)\C(=N\c3ccccc3)\[O-])C(C)C)CC[C@@H](O)C[C@@H](O)CC(=O)[O-].O.O.O
InChI
1S/2C33H35FN2O5.Ca.3H2O/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;3*1H2/q;;+2;;;/p-2/t2*26-,27-;;;;/m11..../s1
InChI key
SHZPNDRIDUBNMH-NIJVSVLQSA-L
grade
pharmaceutical primary standard
API family
atorvastatin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
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General description
本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。想获得更多信息和支持，请访问颁布药典的网站。
阿托伐他汀钙是HMG-CoA还原酶的选择性合成抑制剂。它不溶于pH低于4的水性溶液，易溶于甲醇。
阿托伐他汀钙是HMG-CoA还原酶的选择性合成抑制剂。它不溶于pH低于4的水性溶液，易溶于甲醇。
Application
阿托伐他汀钙USP标准物质可用于指定的质量检测和分析。
也可根据以下美国药典专题用于制备测定和杂质分析用的系统适用性、标准物质、系统适用性储备、鉴定和标准物质储备溶液：
也可根据以下美国药典专题用于制备测定和杂质分析用的系统适用性、标准物质、系统适用性储备、鉴定和标准物质储备溶液：
- 阿托伐他汀钙
- 阿托伐他汀钙片
- 氨氯地平阿托伐他汀片
Analysis Note
这些产品仅供测试和化验使用。它们不适用于人类或动物，也不能用于诊断、治疗或治愈任何类型的疾病。
Other Notes
可能适用相应的销售限制。
flash_point_f
Not applicable
flash_point_c
Not applicable
target_organs
Liver
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - STOT RE 2
存储类别
11 - Combustible Solids
Atorvastatin Calcium Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(1), 418-418 (2020)
Atorvastatin Calcium
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 35(1), 414-414 (2022)
Min-Soo Kim et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 454-465 (2008-03-25)
In this work, amorphous atorvastatin calcium nanoparticles were successfully prepared using the supercritical antisolvent (SAS) process. The effect of process variables on particle size and distribution of atorvastatin calcium during particle formation was investigated. Solid state characterization, solubility, intrinsic dissolution
Yanli Wang et al.
Histology and histopathology, 29(12), 1593-1600 (2014-08-01)
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Shen Li et al.
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