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Merck
CN

1043706

USP

天冬甜素

United States Pharmacopeia (USP) Reference Standard

别名:

天冬酰-苯丙氨酸甲酯, N-(L-α-天冬氨酰)- L -苯丙氨酸甲酯, 天冬甜素, 阿斯巴甜

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关于此项目

线性分子式:
HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
化学文摘社编号:
分子量:
294.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2223850
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产品名称

天冬甜素, United States Pharmacopeia (USP) Reference Standard

SMILES string

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O

InChI key

IAOZJIPTCAWIRG-QWRGUYRKSA-N

InChI

1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1

grade

pharmaceutical primary standard

API family

aspartame

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Aspartame USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M M Garriga et al.
Annals of allergy, 61(6 Pt 2), 63-69 (1988-12-01)
Aspartame is a food additive marketed under the brand name Nutrasweet. Aspartame is a white, odorless, crystalline powder and consists of two amino acids, L-aspartic acid and L-phenylalanine. It is 180 times as sweet as sugar. The Food and Drug
A B Edmundson et al.
Clinical pharmacology and therapeutics, 63(5), 580-593 (1998-06-19)
The binding of sweet-tasting compounds in a human (Mcg) Bence-Jones dimer has been characterized by x-ray crystallography. Aspartame binding in this immunoglobulin fragment is remarkable. Unexpected pain relief noted by A.B.E., a crystallographer with diagnosed osteoarthritis, suggested that the accommodation
R B Kanarek
Nutrition reviews, 52(5), 173-175 (1994-05-01)
Anecdotal evidence has led to the hypothesis that there is a relationship between sugar intake and hyperactive behavior. To assess this hypothesis, a recent study using a range of behavioral and cognitive measures evaluated the effects of diets high in
J D Fernstrom
Appetite, 11 Suppl 1, 35-41 (1988-01-01)
The ingestion of a meal of carbohydrates by fasting rats rapidly increases brain tryptophan level and serotonin (5-HT) synthesis. The rise in brain tryptophan level follows from an increase in tryptophan transport into brain, the consequence of an insulin-induced reduction
P J Janssen et al.
Toxicology, 50(1), 1-26 (1988-06-01)
In this report the neurotoxicity of aspartame and its constituent amino acids aspartic acid and phenylalanine is reviewed. The adverse reactions ascribed to the consumption of aspartame-containing products, as reported in the U.S.A., are discussed and placed in perspective with

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