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Merck
CN

1021204

USP

4-氨基苯酚

United States Pharmacopeia (USP) Reference Standard

别名:

4-羟苯胺

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About This Item

线性分子式:
H2NC6H4OH
CAS号:
分子量:
109.13
Beilstein:
385836
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

paracetamol, acetaminophen, mesalazine

制造商/商品名称

USP

mp

185-189 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Nc1ccc(O)cc1

InChI

1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2

InChI key

PLIKAWJENQZMHA-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis.

应用

This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:
  • Mesalamine
  • Acetaminophen Tablets
  • Acetaminophen Oral Suspension
  • Tramadol Hydrochloride and Acetaminophen Tablets

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

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说明
价格

警示用语:

Warning

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2

靶器官

Kidney

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

危险化学品

分析证书(COA)

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Mesalamine
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(6), 2800-2800 (2020)
Acetaminophen Oral Suspension
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(6), 42-42 (2021)
Acetaminophen tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 45-45 (2021)
Tramadol Hydrochloride and Acetaminophen Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(1), 4450-4450 (2017)
Soumabha Bag et al.
Analytica chimica acta, 860, 37-42 (2015-02-16)
Ionization of aliphatic and aromatic aldehydes is improved by performing simultaneous chemical derivatization using 4-aminophenol to produce charged iminium ions during paper spray ionization. Accelerated reactions occur in the microdroplets generated during the paper spray ionization event for the tested

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