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Merck
CN

1019701

USP

阿米洛利 盐酸盐 二水合物

United States Pharmacopeia (USP) Reference Standard

别名:

N-脒基-3,5-二氨基-6-氯吡嗪甲酰胺盐酸盐 盐酸盐 二水合物

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About This Item

经验公式(希尔记法):
C6H8ClN7O · HCl · 2H2O
CAS号:
分子量:
302.12
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

amiloride

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

InChI

1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2

InChI key

LTKVFMLMEYCWMK-UHFFFAOYSA-N

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一般描述

Amiloride hydrochloride is a photosensitive yellow powder used as a mild diuretic drug.

应用

Amiloride hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Amiloride Hydrochloride and Hydrochlorothiazide Tablets
  • Amiloride Hydrochloride Tablets

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Novel molecular platforms for epithelial sodium channel (ENaC) modulators are claimed in the following six patents: WO2012035158(A1); WO2009074575(A2); WO2011028740(A1); WO2009150137(A2); WO2011079087(A1); WO2008135557(A1). These ENaC inhibitors may be used in blocking transepithelial sodium and consequently water absorption across airway epithelia. This
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The use of multivariate spectrophotometric calibration for the simultaneous analysis of synthetic samples and commercial tablet preparations containing hydrochlorothiazide (HCT) and amiloride hydrochloride (AMH) is reported. Partial least squares (PLS-1) analysis of electronic absorption spectral data allowed the rapid and
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American journal of physiology. Regulatory, integrative and comparative physiology, 306(5), R315-R327 (2014-01-10)
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