InChI key
ZDYJWDIWLRZXDB-UHFFFAOYSA-N
InChI
1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H
grade
analytical standard
packaging
ampule of 50 mg
manufacturer/tradename
Chem Service, Inc. PS-695
application(s)
agriculture
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Anna A Kasperlik-Zaluska et al.
Journal of experimental therapeutics & oncology, 5(2), 125-132 (2006-02-14)
Our study aimed at evaluation of the relations between the plasma levels of mitotane (o,p'-DDD) and its metabolites, o,p'-DDA and o,p'-DDE, and the efficacy of Mitotane therapy during a long-term follow-up. Eighteen patients, aged 11 to 70 years, were included
Ilse G Hermsen et al.
The Journal of clinical endocrinology and metabolism, 96(6), 1844-1851 (2011-04-08)
In patients with adrenocortical carcinoma (ACC) mitotane activity has been suggested to depend on plasma levels 14 mg/liter or greater and metabolite formation. The study was performed to confirm the correlation of the currently used mitotane (o,p'DDD) threshold of 14
P Balaguer et al.
The Science of the total environment, 233(1-3), 47-56 (1999-09-24)
In order to characterize the estrogenic activity of chemicals, we established complementary in vitro recombinant receptor-reporter gene assays in stably transfected MCF-7 and HeLa cells. MCF-7 cells which express the endogenous estrogen receptor alpha (ER alpha) were stably transfected with
D B Carlson et al.
Environmental health perspectives, 108(3), 249-255 (2000-03-08)
Fish sexual development is sensitive to exogenous hormone manipulation, and salmonids have been used extensively as environmental sentinels and models for biomedical research. We simulated maternal transfer of contaminants by microinjecting rainbow trout (Oncorhynchus mykiss) and chinook salmon (Oncorhynchus tshawytscha)
R Benecke et al.
European journal of clinical pharmacology, 41(3), 259-261 (1991-01-01)
Mitotane (o,p'-DDD) can be used for the treatment of various adrenocortical diseases such as Cushing's syndrome, but the usual doses of 6-8 g per day are often associated with severe adverse effects. This paper reports the results of much lower
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