推荐产品
等级
primary reference standard
产品线
phyproof® Reference Substance
方案
≥95.0% (HPLC)
表单
solid
制造商/商品名称
PhytoLab
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
cannabis testing
包装形式
neat
SMILES字符串
OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI
1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2
InChI key
YDQWDHRMZQUTBA-UHFFFAOYSA-N
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一般描述
Aloe-emodin, an anthraquinone derivative, is an active constituent of several medicinal plants. It shows gastrointestinal effects by exerting laxative activity.
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
应用
Aloe-emodin may be used as an analytical reference standard for the determination of the analyte in plant and animal samples by high-performance liquid chromatography technique.
生化/生理作用
复方泻药/泻药；通过释放内源性乙酰胆碱来增加肠道平滑肌的收缩。抗肿瘤活性与活性氧簇 (ROS) 产生增加相关，活性氧簇反过来降低线粒体跨膜电位，从而诱导渗透性转换，启动一系列事件，最终导致细胞凋亡。遗传毒性和致突变性似乎是由于芦荟大黄素抑制了拓扑异构酶II的活性。
其他说明
This compound is commonly found in plants of the genus: aloe
法律信息
phyproof is a registered trademark of PhytoLab GmbH & Co. KG
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry
ElSohly MA, et al.
International Immunopharmacology, 4(14), 1739-1744 (2004)
Simultaneous determination and pharmacokinetic studies of aloe emodin and chrysophanol in rats after oral administration of Da-Cheng-Qi decoction by high-performance liquid chromatography
Tang WF, et al.
Biomedical Chromatography, 21(7), 701-707 (2007)
One single standard substance for the determination of multiple anthraquinone derivatives in rhubarb using high-performance liquid chromatography-diode array detection
Gao XY, et al.
Journal of Chromatography A, 1216(11), 2118-2123 (2009)
Simultaneous determination of five anthraquinones in medicinal plants and pharmaceutical preparations by HPLC with fluorescence detection
He D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(4), 1123-1127 (2009)
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