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Merck
CN

PHL83525

Morusin

phyproof® Reference Substance

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别名:
2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)-4H,8H-benzo[1,2-b:3,4-b′]dipyran-4-one, Mulberrochromene
经验公式(希尔记法):
C25H24O6
CAS号:
分子量:
420.45
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

primary reference standard

产品线

phyproof® Reference Substance

检测方案

≥90.0% (HPLC)

制造商/商品名称

PhytoLab

应用

food and beverages

格式

neat

储存温度

2-8°C

InChI

1S/C25H24O6/c1-13(2)5-7-17-22(29)21-19(28)12-20-16(9-10-25(3,4)31-20)24(21)30-23(17)15-8-6-14(26)11-18(15)27/h5-6,8-12,26-28H,7H2,1-4H3

InChI key

XFFOMNJIDRDDLQ-UHFFFAOYSA-N

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

应用


  • Anti-fatigue properties: Morusin is studied for its role in combating fatigue. The research explores its bioguided isolation and bioactivity, suggesting potential applications in health supplements for enhanced physical performance and resilience (Chen et al., 2024).

  • Anti-cancer activity in breast cancer: Morusin has been found to inhibit breast cancer-induced osteolysis by targeting the PI3K-mTOR signaling pathway, showcasing its therapeutic potential in cancer treatment (Zhang et al., 2024).

  • Aortic valve calcification: Research demonstrates Morusin′s ability to alleviate aortic valve calcification by inhibiting senescence in valve interstitial cells through the Ccnd1/Trim25/Nrf2 axis, highlighting its potential in cardiovascular disease management (Liu et al., 2024).

  • Suppression of gastric cancer cell stemness: Morusin is effective in suppressing the stemness characteristics of gastric cancer cells under hypoxic conditions by inhibiting HIF-1α accumulation, providing insights into its use in limiting cancer progression (Chen et al., 2024).

  • Chemo-photothermal therapy: A Morusin-Cu(II)-indocyanine green nanoassembly has been developed for cancer therapy, igniting mitochondrial dysfunction and enhancing the therapeutic outcomes of chemo-photothermal treatment strategies (Ran et al., 2024).


法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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