产品名称
TSKgel® SuperSW mAb HTP Guard Column, phase diol, L × I.D. 2 cm × 3 mm, 4 μm particle size
material
stainless steel
agency
suitable for USP L20
suitable for USP L59
product line
TSKgel®
manufacturer/tradename
Tosoh SuperSW mAb HTP Guard Column, 22858
parameter
≤0.5 M salt concentration
0-100% aqueous soluble organic solvents
0.5 mL/min flow rate
10-30 °C temperature
technique(s)
HPLC: suitable
L × I.D.
2 cm × 3 mm
matrix
silica particle platform
matrix active group
diol phase
particle size
4 μm
pore size
250 Å pore size
operating pH
2.5-7.5
separation technique
size exclusion (SEC)
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General description
The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best for aggregation, dimer, and fragmentation, making it the best method for heterogeneity studies.TSKgel SuperSW mAb HTP columns provide high throughput analysis of mAb monomer and dimer and is UHPLC compatible. These short, narrow bore (15 cm x 4.6 mm ID) silica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The TSKgel SW mAb HTP columns utilize a unique pore-controlled technology, which produces a shallow calibration curve in the molecular weight region of a typical monoclonal antibody.
Physical form
Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.
Legal Information
TSKgel is a registered trademark of Tosoh Corporation
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