product name
SUPELCOSIL ™ LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4 mm
物料
stainless steel column
质量水平
Agency
suitable for USP L60
产品线
SUPELCOSIL™
特点
endcapped
制造商/商品名称
SUPELCOSIL™
包装
1 ea of
标记范围
12.0% carbon loading
参数
≤70 °C temp. limit
400 bar pressure (5801 psi)
技术
HPLC: suitable
长度 × 内径
25 cm × 4 mm
表面积
170 m2/g
表面覆盖度
surface coverage 3.4 μmol/m2
基质
silica gel, spherical particle platform
fully porous particle
基质活性基团
amide, alkyl phase
粒径
5 μm
孔径
120 Å
pH值范围
2-7.5
应用
food and beverages
分离技术
reversed phase
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相关类别
一般描述
SUPELCOSIL LC-ABZ 相具有独特的去活技术，该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行，以及调节流动相的极端 pH 值来抑制硅烷醇活性，就可以在 LC-ABZ 相上获得良好的峰形。
应用
- Determination of active substances in binary mixture antiparasitic veterinary formulations by HPLC: This study showcases the use of the SUPELCOSIL™ LC-ABZ HPLC column for the precise determination of active compounds in veterinary medicine. This application is crucial in ensuring the effectiveness and safety of veterinary drugs. The study highlights the column′s capability to handle complex mixtures in pharmaceutical formulations, demonstrating its effectiveness in both academic research settings and in quality control for pharmaceutical applications (Kulik et al., 2011).
特点和优势
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
法律信息
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Neil C Dias et al.
The Analyst, 128(5), 427-433 (2003-06-07)
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
J G Ufkes et al.
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
Murali Pendela et al.
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
J A López et al.
Journal of chromatography. A, 870(1-2), 105-114 (2000-03-18)
A high-performance liquid chromatographic method with electrochemical detection has been developed for the determination of six 1,4-dihydropyridines: nifedipine, nimodipine, nisoldipine, nicardipine, felodipine and lacidipine. The chromatographic separation was performed using a Supelcosil LC-ABZ+Plus C18 column. A mobile phase of methanol-water
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