product name
SUPELCOSIL ™ LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
Agency
suitable for USP L60
质量水平
特点
endcapped
制造商/商品名称
SUPELCOSIL™
标记范围
12.0% carbon loading
参数
≤70 °C temp. limit
400 bar pressure (5801 psi)
技术
HPLC: suitable
长度 × 内径
25 cm × 4.6 mm
表面积
170 m2/g
表面覆盖度
surface coverage 3.4 μmol/m2
基质
silica gel, spherical particle platform
基质活性基团
amide, alkyl phase
粒径
5 μm
孔径
120 Å
pH值范围
2-7.5
应用
food and beverages
分离技术
reversed phase
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相关类别
一般描述
SUPELCOSIL LC-ABZ 相具有独特的去活技术，该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行，以及调节流动相的极端 pH 值来抑制硅烷醇活性，就可以在 LC-ABZ 相上获得良好的峰形。
特点和优势
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
法律信息
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Neil C Dias et al.
The Analyst, 128(5), 427-433 (2003-06-07)
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
J G Ufkes et al.
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
D Korakas et al.
Journal of pharmaceutical and biomedical analysis, 12(9), 1141-1145 (1994-09-01)
A series of biologically active peptides and their conjugates with lipidic amino acids were investigated by systematic change of the mobile phase composition using traditional octadecylsilica stationary phase and the newly developed Supelcosil LC-ABZ column. The mobile phases contained various
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