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UNSPSC Code:
41115700
eCl@ss:
32110501
EC Number:
231-545-4
NACRES:
SB.52
L × i.d.:
15 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
amide, alkyl phase
Pore size:
120 Å
Matrix:
silica gel, spherical particle platform, fully porous particle
产品名称
SUPELCOSIL ™ LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
agency
suitable for USP L60
product line
SUPELCOSIL™
feature
endcapped
manufacturer/tradename
SUPELCOSIL™
packaging
1 ea of
extent of labeling
12.0% carbon loading
parameter
≤70 °C temp. limit, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
15 cm × 4.6 mm
surface area
170 m2/g
surface coverage
surface coverage 3.4 μmol/m2
matrix
silica gel, spherical particle platform, fully porous particle
matrix active group
amide, alkyl phase
particle size
5 μm
pore size
120 Å
pH range
2-7.5
application(s)
food and beverages
separation technique
reversed phase
Quality Level
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General description
SUPELCOSIL LC-ABZ 相具有独特的去活技术,该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行,以及调节流动相的极端 pH 值来抑制硅烷醇活性,就可以在 LC-ABZ 相上获得良好的峰形。
Application
- 奈韦拉平原料药中相关有机杂质的高效液相色谱检测方法的验证。:本文验证了使用SUPELCOSIL™ LC-ABZ HPLC色谱柱评估HIV药物纯度和杂质的方法,展示了该色谱柱的高特异性和重现性(Li et al., 2000)。
- S-腺苷-L-蛋氨酸及其相关代谢物在Hypersil ODS和Supelcosil LC-ABZ固定相上的反相HPLC保留行为的比较研究。:这项比较研究深入探讨了生物活性化合物在SUPELCOSIL™ LC-ABZ上的保留行为,肯定了其在复杂生化分离中的通用性和强大性能(Valkó et al., 1993)。
Features and Benefits
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Neil C Dias et al.
The Analyst, 128(5), 427-433 (2003-06-07)
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
J G Ufkes et al.
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
K Valkó et al.
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
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