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Merck
CN

59140-U

SUPELCOSIL LC-ABZ (5 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

别名:

氨基苯系物HPLC色谱柱

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关于此项目

UNSPSC Code:
41115700
eCl@ss:
32110501
EC Number:
231-545-4
NACRES:
SB.52
L × i.d.:
15 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
amide, alkyl phase
Pore size:
120 Å
Matrix:
silica gel, spherical particle platform, fully porous particle
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产品名称

SUPELCOSIL LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

agency

suitable for USP L60

product line

SUPELCOSIL

feature

endcapped

manufacturer/tradename

SUPELCOSIL

packaging

1 ea of

extent of labeling

12.0% carbon loading

parameter

≤70 °C temp. limit, 400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

15 cm × 4.6 mm

surface area

170 m2/g

surface coverage

surface coverage 3.4 μmol/m2

matrix

silica gel, spherical particle platform, fully porous particle

matrix active group

amide, alkyl phase

particle size

5 μm

pore size

120 Å

pH range

2-7.5

application(s)

food and beverages

separation technique

reversed phase

Quality Level

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General description

SUPELCOSIL LC-ABZ 相具有独特的去活技术,该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行,以及调节流动相的极端 pH 值来抑制硅烷醇活性,就可以在 LC-ABZ 相上获得良好的峰形。

Application


  • 奈韦拉平原料药中相关有机杂质的高效液相色谱检测方法的验证。:本文验证了使用SUPELCOSIL LC-ABZ HPLC色谱柱评估HIV药物纯度和杂质的方法,展示了该色谱柱的高特异性和重现性(Li et al., 2000)。

  • S-腺苷-L-蛋氨酸及其相关代谢物在Hypersil ODS和Supelcosil LC-ABZ固定相上的反相HPLC保留行为的比较研究。:这项比较研究深入探讨了生物活性化合物在SUPELCOSIL LC-ABZ上的保留行为,肯定了其在复杂生化分离中的通用性和强大性能(Valkó et al., 1993)。

Features and Benefits

• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物,峰形、柱效和保留性相当于 C8 相

Other Notes

发现适用于高效液相色谱液相色谱-质谱分析的理想LiChropur试剂

Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

存储类别

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Neil C Dias et al.
The Analyst, 128(5), 427-433 (2003-06-07)
The solvation parameter model is used to identify suitable chromatographic models for estimating the octanol-water partition coefficient for neutral compounds of varied structure by reversed-phase liquid chromatography. The stationary phase Supelcosil LC-ABZ with methanol-water mobile phases affords a series of
J G Ufkes et al.
Pharmacy world & science : PWS, 20(2), 83-87 (1998-05-19)
To study the pharmacokinetics of dextromoramide in long-term opiate addicts on methadone maintenance therapy (MMT) a reverse-phase HPLC technique was developed to monitor dextromoramide and methadone concentrations in plasma simultaneously. After liquid-liquid extraction from plasma, dextromoramide and methadone were determined
K Valkó et al.
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities

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