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Merck
CN

58358

SUPELCOSIL LC-18-DB (5 µm) HPLC Columns

L × I.D. 25 cm × 10 mm, HPLC Column

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UNSPSC Code:
41115700
eCl@ss:
32110501
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产品名称

SUPELCOSIL LC-18-DB HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 10 mm

agency

suitable for USP L1

feature

endcapped

manufacturer/tradename

SUPELCOSIL

extent of labeling

11.0% Carbon loading

parameter

0-70 °C temperature
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

25 cm × 10 mm

surface area

170 m2/g

surface coverage

surface coverage 3.1 μmol/m2

matrix

silica gel, spherical particle platform

matrix active group

C18 (octadecyl) phase

particle size

5 μm

pore size

120 Å

application(s)

food and beverages

separation technique

reversed phase

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General description

SUPELCOSIL LC- DB 类的键合相针对碱性化合物进行了特殊的去活化处理。与其它 A 型硅胶反相色谱柱相比,分析有机碱时该色谱柱保留时间更短、峰形更好和柱效更高。

Application

SUPELCOSIL LC-18-DB HPLC Column has been used for the separation of:
  • Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).
  • Uracil in aqueous solutions during its separation by reversed phase high performance liquid chromatography equipped with ultraviolet-visible (UV-Vis) detection.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

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Characterisation of reversed-phase liquid chromatographic columns by chromatographic tests. Evaluation of 36 test parameters: repeatability, reproducibility and correlation.
Visky D, et al.
Journal of Chromatography A, 977(1), 39-58 (2002)
Ce Li et al.
American journal of physiology. Gastrointestinal and liver physiology, 320(3), G380-G395 (2021-01-28)
Pancreatic ductal adenocarcinoma (PDAC) is highly metastatic and represents one of the deadliest forms of human cancers. Previous studies showed that activation of Yes-associated protein 1 (YAP1) plays a key role in malignant transformation in the pancreas. In this study
Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis
Euerby MR and Petersson P
Journal of Chromatography A, 994(1-2), 13-36 (2003)
M Carini et al.
Journal of pharmaceutical and biomedical analysis, 18(1-2), 201-211 (1998-12-24)
A study was undertaken for the characterization and quantitative determination of the main urinary metabolites of the non-steroidal anti-inflammatory drug (NSAID) nimesulide (4-nitro-2-phenoxy-methanesulfonanilide) in man following single oral administration (200 mg). Urines were collected from six healthy volunteers at 12
Xinghua Sun et al.
Anticancer research, 25(1A), 59-62 (2005-04-09)
A rapid, sensitive and specific high-performance liquid chromatographic (HPLC) method for the separation and quantification of L-methionine in plasma has been developed. After derivatization of plasma amino acids with o-phthalaldehyde (OPA), a 50 microl sample was loaded on a reversed-phase

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