推荐产品
产品名称
SUPELCOSIL™ LC-CN HPLC 柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
物料
stainless steel column
质量水平
Agency
suitable for USP L10
产品线
SUPELCOSIL™
特点
endcapped
包装
1 ea of
标记范围
4% Carbon loading
参数
≤70 °C temp. range
技术
HPLC: suitable
长度 × 内径
15 cm × 4.6 mm
表面积
170 m2/g
表面覆盖度
surface coverage 3.5 μmol/m2
基质
silica gel, spherical particle platform
fully porous particle
基质活性基团
cyano phase
粒径
5 μm
孔径
120 Å
pH值范围
2-7.5
分离技术
hydrophilic interaction (HILIC)
normal phase
reversed phase
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一般描述
LC-CN 相通常作为硅胶相的替代者,因为它具有键合相的优点(例如快速平衡,以及对于流动相中水分含量的微小变化更不敏感)。然而 LC-CN 柱通常是在反相的流动相条件下运行。
应用
- 经验证可用于人血浆中霉酚酸(MPA)监测的简单HPLC-UV方法。内标法::本研究提出了一种经验证可用于监测人血浆中霉酚酸的HPLC-UV方法。研究重点介绍了内标法在实现精确定量方面的必要性和效率。(Kunicki PK et al., 2021)。
- 一种改进的HPLC方法,用于人血浆中治疗药物柔红霉素、伊达比星、阿霉素、表柔比星及其13-二氢代谢物的监测。:本文介绍了一种用于监测人血浆中几种化疗药物及其代谢物治疗水平的增强型HPLC方法,提高了药物监测的准确性和可靠性。(Fogli S et al., 1999)。
- 高效液相色谱法分析血清中的地尔硫卓和去乙酰地尔硫卓。:研究侧重于建立分析血清中地尔硫卓及其主要代谢物的HPLC方法,为临床药代动力学研究提供了强有力的工具。(Paczkowski D et al., 1995)。
- 高效液相色谱法测定尿液中依氯那明及其N-去甲基和N,N-二去甲基代谢物。:研究详细介绍了一种用于测定尿液中依氯那明及其代谢物的高效液相色谱方法,这对药代动力学和毒理学分析至关重要。(Lakings DB et al., 1988)。
法律信息
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Polish journal of pharmacology, 47(5), 429-434 (1995-09-01)
This paper describes a simple high-performance liquid chromatographic (HPLC) method for the determination of diltiazem and desacetyldiltiazem in human serum. After basic methyl-tert-butyl ether extraction and back-extraction with hydrochloric acid, the drug and its metabolite was injected into a Supelcosil
Therapeutic drug monitoring, 21(3), 367-375 (1999-06-12)
A single high-performance liquid chromatography (HPLC) method, suitable for the analysis of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites is validated in the present study. Preparation of plasma samples was performed by a first extraction of analytes with a
Journal of analytical toxicology, 24(4), 257-265 (2000-06-29)
A simple and rapid method for the determination of amphetamine, methamphetamine, and their 3,4-methylenedioxy derivatives in urine samples was developed using automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS). In-tube SPME is an extraction technique
Journal of chromatography. B, Biomedical sciences and applications, 731(2), 353-359 (1999-10-08)
The technique of automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) was evaluated for the determination of ranitidine. In-tube SPME is an extraction technique for organic compounds in aqueous samples, in which analytes are extracted
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