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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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安全信息

567501-U

Supelco

Discovery® HS F5 (3 µm) HPLC Columns

L × I.D. 3.3 cm × 2.1 mm, HPLC Column

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选择尺寸

1 EA
¥5,177.25

¥5,177.25


预计发货时间2025年5月27日详情



选择尺寸

变更视图
1 EA
¥5,177.25

About This Item

UNSPSC代码:
41115700
eCl@ss:
32110501
NACRES:
SB.52

¥5,177.25


预计发货时间2025年5月27日详情


产品名称

Discovery ® HS F5 HPLC 色谱柱, 3 μm particle size, L × I.D. 3.3 cm × 2.1 mm

物料

stainless steel column

Agency

suitable for USP L43

产品线

Discovery®

特点

endcapped

制造商/商品名称

Discovery®

包装

1 ea of

标记范围

12% Carbon loading

参数

≤70 °C temp. range
400 bar pressure (5801 psi)

技术

HPLC: suitable
LC/MS: suitable

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567532U567531U567502U
separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

matrix active group

PFP (pentafluorophenyl) phase

matrix active group

PFP (pentafluorophenyl) phase

matrix active group

PFP (pentafluorophenyl) phase

matrix active group

PFP (pentafluorophenyl) phase

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

agency

suitable for USP L43

agency

suitable for USP L43

agency

suitable for USP L43

agency

suitable for USP L43

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

一般描述

将 C18 柱方法转换至 Discovery® HS F5 柱的指导原则:
通常,碱性化合物在 HS F5 色谱柱上的保留时间比在 C18 柱上更长。在 C18 柱上流动相中的有机相含量提高 5% 至 10% 通常可获得与 HS F5 柱类似的保留值。使用其他化合物所得的结果差异则很大。然而 log Po/w 值小于 2.5 的化合物在 HS F5 柱上的保留时间通常要长于 C18 柱。保留时间的差异程度与化合物的 logP o/w 值密切相关。
Discovery® HS F5 键合相可提供与 C18 色谱柱截然不同的反相分离。由于 F5 色谱柱上各种化合物通常会在与 C18 相同的时间范围内洗脱出来,使得大部分的 C18 方法可轻松转换到 F5 上。

特点和优势

  • 独特的选择性
  • 保留能力与 C18 柱类似(有时需要洗脱能力更强的流动相)
  • 峰形极佳
  • 稳定性好、低流失,适用于 LC-MS 分析
  • 粒径范围从 3μm 到 10μm 可供选择

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法律信息

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Federica Pellati et al.
    Journal of pharmaceutical and biomedical analysis, 48(2), 254-263 (2007-12-14)
    In this study a pentafluorophenylpropyl (PFPP) stationary phase was applied to the fast and reliable qualitative and quantitative analysis of ephedrine alkaloids in Ephedra plant material and derivatives. A Discovery HS F5 column (150mmx4.6mm i.d., 5microm) was used, with an
    Koji Baba et al.
    Journal of chromatography. A, 1354, 109-116 (2014-06-21)
    Arsenic species, including arsenous acid, arsenic acid, methylarsonic acid, and dimethylarsinic acid, were determined using HPLC-ICPMS. The species were separated with a Discovery HS F5 column and a simple, volatile, and isocratic mobile phase of 0.1% (v/v) formic acid and
    Ilia Brondz et al.
    Journal of pharmaceutical and biomedical analysis, 43(3), 937-944 (2006-11-03)
    The drug primaquine diphosphate is used for causative treatment of malaria. Using HPLC-MS and GC-MS, this research group was previously able to show that the main contaminant of primaquine is the positional isomer quinocide [I. Brondz, D. Mantzilas, U. Klein
    Federica Pellati et al.
    Journal of chromatography. A, 1165(1-2), 58-66 (2007-08-07)
    In this study, the chromatographic performance of a pentafluorophenylpropyl (PFPP) stationary phase was evaluated for the rapid separation of phenethylamine alkaloids (i.e. (+/-)-octopamine, (+/-)-synephrine, tyramine, N-methyltyramine and hordenine) in Citrus aurantium plant material (fruits and peel), various Citrus species, extracts
    Milan Nobilis et al.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(32), 3845-3852 (2011-11-22)
    New bioanalytical SPE-HPLC-PDA-FL method for the determination of the neuroleptic drug tiapride and its N-desethyl metabolite was developed, validated and applied to xenobiochemical and pharmacokinetic studies in humans and animals. The sample preparation process involved solid-phase extraction of diluted plasma

    相关内容

    Discovery® HPLC Columns for Fast LC-MS Analysis. The Discovery LC-MS line offers short length columns for fast LC-MS analysis that are rugged and dependable. Supelco offers a robust product that withstands column shock due to fast gradient turnaround times.

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