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Merck
CN
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文件

53542-U

Supelco

Ascentis® Express Peptide 160 Å ES-C18 (2.7 μm) HPLC Columns

L × I.D. 5 mm × 4.6 mm, HPLC Guard Cartridge, pkg of 3 ea

别名:

Superficially Porous Wide Pore C18 Guard Column

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About This Item

UNSPSC代码:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express Peptide ES C18 保护柱芯, 2.7 μm particle size, L × I.D. 5 mm × 4.6 mm, pkg of 3 ea

物料

stainless steel column

质量水平

100

Agency

suitable for USP L1

产品线

Ascentis®

特点

endcapped: no

包装

pkg of 3 ea

标记范围

4.6% carbon loading

技术

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

长度 × 内径

5 mm × 4.6 mm

表面积

90 m2/g

基质

superficially porous particle

基质活性基团

C18 (octadecyl) phase

粒径

2.7 μm

孔径

160 Å

工作pH值

1-9

分离技术

reversed phase

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相关类别

一般描述

Ascentis Express Guard Columns provide physical (filtration) and chemical protection for costly analytical columns without compromising the very high performance of Ascentis Express columns. These Ascentis Express guard columns are capable of continuous use at pressures up to 9000 psi (600 bar) with only hand-tightening. Guard cartridges are easily replaced without removing the guard column holder from the flow path. The cartridges are packed with Ascentis Express Fused-Core®particles. Order guard column holder (53500-U) separately.

应用


  • Proteotypic Peptide Identification in Biosynthetic Insulin: Utilizes Ascentis® Express Peptide ES-C18, 2.7 μm Guard Cartridge in multiplexed targeted mass spectrometry to identify proteotypic tryptic peptides of recombinant human insulin and biosynthetic insulin analogues, demonstrating high resolution and precision in peptide mapping essential for biopharmaceutical analysis (Qasem et al., 2019).

  • Preclinical Pharmacokinetic Study of Thymopentin: Employs the Ascentis® Express Peptide ES-C18, 2.7 μm Guard Cartridge for the high-resolution separation and quantitative determination of thymopentin in beagle dog blood, highlighting its application in pharmacokinetic studies and drug development (Shi et al., 2015).

  • Cytochrome P450 and UDP-Glucuronosyltransferases Quantification: Features the use of Ascentis® Express Peptide ES-C18, 2.7 μm Guard Cartridge in a targeted proteomics approach for the absolute quantification of clinically relevant enzymes, offering insights into protein expression levels critical for drug metabolism and pharmacogenomics studies (Gröer et al., 2014).

  • Carotenoid Analysis in Superficially Porous Phases: Demonstrates the capability of the Ascentis® Express Peptide ES-C18, 2.7 μm Guard Cartridge in extending the carotenoid test to new stationary phases, underlining its versatility and effectiveness in analytical chromatography for complex natural products (Lesellier, 2012).

法律信息

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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