推荐产品
product name
Ascentis® Express RP-Amide，2.7 μm保护柱芯, 2.7 μm particle size, L × I.D. 5 mm × 4.6 mm, pkg of 3 ea
物料
stainless steel column
质量水平
Agency
suitable for USP L60
产品线
Ascentis®
特点
endcapped
包装
pkg of 3 ea
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
5 mm × 4.6 mm
表面积
135 m2/g
基质
Fused-Core® particle platform
superficially porous particle
基质活性基团
amide, alkyl phase
粒径
2.7 μm
孔径
90 Å
工作pH值
2-9
应用
food and beverages
分离技术
reversed phase
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相关类别
一般描述
Ascentis Express保护柱可为昂贵的分析柱提供物理（过滤）和化学保护，而不会损害Ascentis Express柱的超高性能。这些Ascentis Express保护柱仅需用手拧紧即可在高达9000 psi（600 bar）的压力下连续使用。无需从流路中卸下保护柱套即可轻松更换保护柱芯。柱芯中填充有Ascentis Express Fused-Core®颗粒。单独订购保护柱套。
应用
- Polycaprolactone Composite Micro/Nanofibrous Material as an Alternative to Restricted Access Media for Direct Extraction and Separation of Non-Steroidal Anti-Inflammatory Drugs from Human Serum Using Column-Switching Chromatography: This research utilized the Ascentis Express RP-Amide, demonstrating its effectiveness in column-switching chromatography for the extraction and separation of non-steroidal anti-inflammatory drugs directly from human serum. The study highlights the column′s utility in handling complex biological matrices, an essential aspect for pharmacokinetic and drug monitoring studies (Raabova et al., 2021).
- An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study: This paper details the use of the Ascentis Express RP-Amide in a validated HPLC-MS method for the analysis of PC 48, a novel acetylcholinesterase inhibitor, in rat plasma. The method′s application to pharmacokinetic studies underscores its significance in the development and therapeutic monitoring of new drugs (Mzik et al., 2016).
- On-line SPE-UHPLC method using fused core columns for extraction and separation of nine illegal dyes in chilli-containing spices: Demonstrating the versatility of the Ascentis Express RP-Amide, this study employed the column in an on-line solid-phase extraction (SPE) coupled with UHPLC to detect illegal dyes in food samples. The method′s robustness and high-throughput capabilities make it ideal for ensuring food safety and compliance with regulatory standards (Khalikova et al., 2014).
法律信息
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Michael T Furlong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 926, 36-41 (2013-04-02)
Clopidogrel is prescribed for the treatment of Acute Coronary Syndrome and recent myocardial infarction, recent stroke, or established peripheral arterial disease. A sensitive and reliable high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay was developed and validated to enable reliable
Martin Mzik et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1020, 85-89 (2016-04-01)
A simple, rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated for the quantitative determination in rat plasma of a new candidate for AD treatment, namely PC 48 (a 7-MEOTA-donepezil like compound) in
Erzsébet Oláh et al.
Journal of chromatography. A, 1217(23), 3642-3653 (2010-04-23)
Today sub-2 microm packed columns are very popular to conduct fast chromatographic separations. The mass-transfer resistance depends on the particle size but some practical limits exist not to reach the theoretically expected plate height and mass-transfer resistance. Another approach applies
Maria A Khalikova et al.
Talanta, 130, 433-441 (2014-08-28)
The presented work describes the development of a simple, fast and effective on-line SPE-UHPLC-UV/vis method using fused core particle columns for extraction, separation and quantitative analysis of the nine illegal dyes, most frequently found in chilli-containing spices. The red dyes
Fan Sai et al.
Journal of agricultural and food chemistry, 60(8), 1898-1905 (2012-02-15)
A sensitive method has been developed for the simultaneous determination of residues of 25 β₂-agonists and 23 β-blockers in animal foods by high-performance liquid chromatography coupled with linear ion trap mass spectrometry (HPLC-LIT-MS). This method is based on a new
商品
Improve your separation of basic compounds with our Ascentis® Express RP-Amide HPLC columns from the Supelco® portfolio.
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