product name
Ascentis® Express RP- 氨基化合物，5μm HPLC色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
物料
stainless steel column
质量水平
Agency
suitable for USP L60
产品线
Ascentis®
特点
endcapped
制造商/商品名称
Ascentis®
包装
1 ea of
参数
60 °C temp. range
600 bar max. pressure (9000 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
25 cm × 4.6 mm
表面积
90 m2/g
杂质
<5 ppm metals
基质
Fused-Core® particle platform
superficially porous particle
基质活性基团
amide, alkyl phase
粒径
5 μm
孔径
90 Å pore size
pH值范围
2-9
应用
food and beverages
分离技术
reversed phase
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相关类别
一般描述
Ascentis Express 5 μm RP-Amide是一款基于高效熔融核®颗粒设计的高速、高效液相色谱柱。熔融核颗粒提供了围绕固体二氧化硅核的高纯度二氧化硅薄多孔外壳。由于在0.6 μm厚的多孔外壳中的浅扩散途径和5 μm的高度均匀的总粒度，该颗粒设计表现出非常高的柱效。Ascentis Express 5 μm RP-Amide的一步键合、封端、酰胺基、极性嵌入固定相提供了稳定的反相填料，具有降低的疏水性。Ascentis Express RP-Amide可用于具有C18或C8正交选择性的碱性、酸性或中性化合物。极性包埋的Ascentis Express 5 μm RP-Amide色谱柱与100%水性流动相相容，不会出现“相崩溃”。
法律信息
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
法规信息
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1020, 85-89 (2016-04-01)
A simple, rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated for the quantitative determination in rat plasma of a new candidate for AD treatment, namely PC 48 (a 7-MEOTA-donepezil like compound) in
Erzsébet Oláh et al.
Journal of chromatography. A, 1217(23), 3642-3653 (2010-04-23)
Today sub-2 microm packed columns are very popular to conduct fast chromatographic separations. The mass-transfer resistance depends on the particle size but some practical limits exist not to reach the theoretically expected plate height and mass-transfer resistance. Another approach applies
Maria A Khalikova et al.
Talanta, 130, 433-441 (2014-08-28)
The presented work describes the development of a simple, fast and effective on-line SPE-UHPLC-UV/vis method using fused core particle columns for extraction, separation and quantitative analysis of the nine illegal dyes, most frequently found in chilli-containing spices. The red dyes
Hirotaka Kushida et al.
Biomedical chromatography : BMC, 27(12), 1647-1656 (2013-07-03)
Uncaria Hook (UH) alkaloids are involved in the beneficial effects of Yokukansan. However, the pharmacokinetics of UH alkaloids after oral administration of Yokukansan has not yet been sufficiently investigated. Therefore, we developed and validated a sensitive and specific high-performance liquid
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