product name
Discovery® C18 高效液相色谱柱, 5 μm particle size, L × I.D. 15 cm × 4 mm
物料
stainless steel column
质量水平
Agency
suitable for USP L1
产品线
Discovery®
特点
endcapped
制造商/商品名称
Discovery®
包装
1 ea of
标记范围
12% Carbon loading
参数
≤70 °C temp. range
400 bar pressure (5801 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
15 cm × 4 mm
表面积
300 m2/g
表面覆盖度
3 μmol/m2
杂质
<10 ppm metals
基质
silica gel, high purity, spherical particle platform
fully porous particle
基质活性基团
C18 (octadecyl) phase
粒径
5 μm
孔径
180 Å
operating pH range
2-8
应用
food and beverages
分离技术
reversed phase
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相关类别
一般描述
Discovery® C18 可用于针对 C18 的任何方法。该色谱柱具有对称的峰形、优良的重现性和稳定性等特点，适用于所有常规和高要求的 C18 方法，是此类方法的理想选择。
应用
- Determination of 2,4-dimethylhydroxybenzene by chromatographic methods in forensic toxicological research of biological material: This research highlights the Discovery® C18 column′s application in forensic science, providing robust and precise analyses necessary for toxicological screenings (Chernova et al., 2024).
特点和优势
- 优良的重现性
- 分析酸性和碱性化合物均可获得良好的峰形
- 稳定性好、低流失，适用于 LC-MS 分析
- 能够分离多肽和小分子蛋白质
- 与很多同类 C18 色谱柱相比，疏水性更小，因此分析速度更快
法律信息
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
R Nageswara Rao et al.
Biomedical chromatography : BMC, 23(11), 1145-1150 (2009-05-16)
A highly sensitive and selective on-line two-dimensional reversed-phase liquid chromatography/electrospray ionization-tandem mass spectrometry (2D-LC-ESI/MS/MS) method was developed and validated to determine rifaximin in rat serum by direct injection. The 2D-LC-ESI/MS/MS system consisted of a restricted access media column for trapping
Yoshinori Masukawa et al.
Journal of lipid research, 49(7), 1466-1476 (2008-03-25)
Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species might be closely related to the regulation of keratinization, together with other CER-related lipids. Structures of those diverse
Pei Yuan et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(42), 11319-11325 (2009-09-18)
This study systematically investigates periodic mesoporous organosilicas (PMOs) with controlled helical and concentric circular (CC) pore architectures prepared through a basic-catalyzed sol-gel process by using an achiral cationic surfactant trimethyloctadecylammonium bromide (C(18)TAB) as a structure-directing agent, perfluorooctanoic acid (PFOA) as
Pilar Heredia-Middleton et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 149(4), 552-556 (2008-02-01)
Heat shock protein 70 (HSP70, 70 kDa) is the most commonly expressed protein in response to thermal stress. The extent of its expression is associated with differences in environmental temperatures. We investigated the heat shock response in red blood cells
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
相关内容
Discovery C18 and C8 HPLC Columns products offered
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