推荐产品
物料
PE frit (20 μm porosity)
polypropylene hardware
质量水平
产品线
Supelclean™
特点
endcapped
组成
bed wt., 100 mg
包装
pk of 108
标记范围
~11.5% C loading
技术
solid phase extraction (SPE): suitable
表面积
475 m2/g
体积
1 mL
基质
silica gel base material (irregularly shaped)
基质活性基团
C18 (octadecyl) bonding, monomerically bonded
粒径
45 μm
孔径
0.8 cm3/g pore volume
60 Å pore size
应用
food and beverages
分离技术
reversed phase
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一般描述
Supelclean™ LC-18 SPE tube is used in solid phase extraction (SPE) method to extract non-polar to moderately polar compounds from aqueous samples.
应用
Supelclean™ LC-18 SPE Tube may be used for the solid-phase extraction of:
- Artesunate, dihydroartemisinin, mefloquine, amodiaquine and desethylamodiaquine in human plasma samples prior to their determination by reversed phase high performance liquid chromatography (RP-HPLC) coupled to electrochemical (EC) detector or ultraviolet (UV) detector.
- Ursodeoxycholic acid in blood serum samples prior to its analysis by HPLC-UV.
- Calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma samples after oral administration of Danggui Buxue Tang extract, prior to their pharmacokinetic studies by LC coupled to mass spectrometry (MS).
法律信息
Supelclean is a trademark of Sigma-Aldrich Co. LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(5-6), 558-562 (2009)
Simultaneous determination of calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry.
Journal of Chromatography. B, Biomedical Sciences and Applications, 865(1-2), 99-105 (2008)
An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological studies of the drug combination.
Journal of Chromatography. B, Biomedical Sciences and Applications, 857(2), 308-314 (2007)
International journal of molecular sciences, 22(4) (2021-02-13)
The phosphorylation of proteins modulates various functions of proteins and plays an important role in the regulation of cell signaling. In recent years, label-free quantitative (LFQ) phosphoproteomics has become a powerful tool to analyze the phosphorylation of proteins within complex
Journal of pharmaceutical and biomedical analysis, 24(5-6), 937-946 (2001-03-15)
Ursodeoxycholic acid (3 alpha,7 beta-dihydroxy-5 beta-cholanoic acid, UDCA) is a therapeutically applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the treatment of chronic liver diseases associated with cholestasis. UDCA is more hydrophilic and less toxic
商品
Reversed-phase interaction will retain most molecules with hydrophobic character; it is very useful for extracting analytes that are very diverse in structure within the same sample.
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