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Merck
CN

49055

甲基对硫磷

PESTANAL®, analytical standard

别名:

Methyl parathion, O,O-二甲基 O-(4-硝基苯基)硫代磷酸酯

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关于此项目

经验公式（希尔记法）:
C8H10NO5PS
化学文摘社编号:
298-00-0
分子量:
263.21
EC Number:
206-050-1
UNSPSC Code:
41121813
PubChem Substance ID:
24872575
Beilstein/REAXYS Number:
8905814
MDL number:
MFCD00041813

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产品名称

甲基对硫磷, PESTANAL®, analytical standard

InChI

1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

InChI key

RLBIQVVOMOPOHC-UHFFFAOYSA-N

SMILES string

COP(=S)(OC)Oc1ccc(cc1)[N+]([O-])=O

grade

analytical standard

product line

PESTANAL®

CofA

current certificate can be downloaded

packaging

ampule of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

room temp

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Parathion-methyl is an organophosphate insecticide, which is extensively used for agricultural purposes. Its mode of action involves the inactivation of the enzyme acetylcholinesterase (AChE) in insects and also mammals. It undergoes degradation by soil microorganisms to yield p-nitrophenol as the product.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Flam. Liq. 3 - STOT RE 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

114.8 °F - open cup

flash_point_c

46 °C - open cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
LC24640V
LC22545V
LC16218V
LC12144V
LC09422V

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Effect of paraoxon-methyl and parathion-methyl on DNA in human lymphocytes and protective action of vitamin C
Blasiak J and Kowalik J
Pest Management Science, 55(12), 1182-1186 (1999)
Isolation, characterization and identification of methyl parathion degrading bacteria from industrial waste
Vadukia, et al.
Journal of Cell and Tissue Research, 14(3), 4633-4633 (2014)
Absorption, distribution, metabolism and excretion of daily oral doses of [14 C] methyl parathion in hens
Abu-Qare WA, et al.
Toxicology Letters, 125(1), 1-10 (2001)
Mohamed Abdel-Razek Saleh Abdel-Razek et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(6), 449-461 (2013-03-05)
The goal of this study was to optimize methyl parathion (O,O-dimethyl-O-4-p-nitrophenyl phosphorothioate) degradation using a strain of Escherichia coli DH5α expressing the opd gene. Our results indicate that this strain had lower enzymatic activity compared to the Flavobacterium sp. ATCC
Jingming Gong et al.
Biosensors & bioelectronics, 39(1), 320-323 (2012-08-08)
We developed a highly sensitive flow injection/amperometric biosensor for the detection of organophosphate pesticides (OPs) using layered double hydroxides (LDHs) as the immobilization matrix of acetylcholinesterase (AChE). LDHs provided a biocompatible microenvironment to keep the bioactivity of AChE, due to
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