产品名称
N-亚硝基二正丙胺, analytical standard
InChI key
YLKFDHTUAUWZPQ-UHFFFAOYSA-N
InChI
1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
SMILES string
CCCN(CCC)N=O
grade
analytical standard
CofA
current certificate can be downloaded
packaging
ampule of 100 mg
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
storage temp.
2-30°C
Quality Level
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Application
N-亚硝基二正-丙基胺可用作分析参考标准品,用于通过气相色谱-三重四极杆质谱测定废水样品中的分析物。
Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
A new method for quantifying N-nitrosamines in wastewater samples by gas chromatography?triple quadrupole mass spectrometry.
Yoon S, et al.
Talanta, 97, 256-261 (2012)
Development and validation of GC-FID method for the determination of volatile N-nitrosamines in meat
Al-Kaseem M, et al.
International Journal of Pharmaceutical Sciences Review and Research, 25, 59-64 (2014)
J F Teiber et al.
Carcinogenesis, 21(8), 1559-1566 (2000-07-27)
The ability of human liver cytochrome P450s to metabolize the environmental carcinogen N-nitrosodi-n-propylamine (NDPA) was investigated. The maximum rate of NDPA depropylation in seven human liver microsomal samples was 1.15 nmol/min/mg (range 0.53-2.60). Troleandomycin, a P450 3A4/5 inhibitor, inhibited depropylation
E Richter et al.
Carcinogenesis, 7(7), 1207-1213 (1986-07-01)
Possible relationships between structure and metabolism of nitrosamines have been investigated in the rat small intestine. Isolated segments of jejunum and ileum were perfused from the luminal side for 2 h with a Tyrode solution containing one of four symmetrical
N-Nitrosodi-n-propylamine.
Report on carcinogens : carcinogen profiles, 11, III200-III201 (2004-01-01)
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