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Merck
CN
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文件

47775

Supelco

甲萘醌 (K3)

analytical standard

别名:

甲萘醌, 2-甲基-1,4-萘醌, 维生素 K3

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About This Item

经验公式（希尔记法）:
C11H8O2
CAS号:
58-27-5
分子量:
172.18
Beilstein:
1908453
EC 号:
200-372-6
MDL编号:
MFCD00001681
UNSPSC代码:
12164500
PubChem化学物质编号:
24871411

等级

analytical standard

质量水平

100

CofA

current certificate can be downloaded

特点

standard type fat soluble vitamin

包装

ampule of 1000 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

105-107 °C (lit.)

应用

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

格式

neat

储存温度

2-30°C

SMILES字符串

CC1=CC(=O)c2ccccc2C1=O

InChI

1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3

InChI key

MJVAVZPDRWSRRC-UHFFFAOYSA-N

基因信息

human ... NQO1(1728)

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相关类别

一般描述

甲萘醌是一种促血栓形成的化合物，属于维生素K类化合物，其对于凝血酶原和其他凝血因子的生物合成是必不可少的。它可用作细胞培养和体内研究中的模型醌。 它是叶绿醌的分解代谢产物，是大鼠组织中甲萘醌4的循环前体。
甲萘醌（K3）是一种脂溶性维生素前体，它是肠中口服叶绿醌（维生素k1）的分解代谢产物。

应用

有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。
甲萘醌（K3）可用作液相色谱技术定量测定生物体液中分析物的分析参考标准品。

象形图

Exclamation markEnvironment
GHS07,GHS09

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
LRAD2358
LRAC4189
LRAC0446
LRAB6871
LC22078V

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Development of a validated liquid chromatography method for the simultaneous determination of eight fat-soluble vitamins in biological fluids after solid-phase extraction
Chatzimichalakis FP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 805(2), 289-296 (2004)
Daiki Habu et al.
JAMA, 292(3), 358-361 (2004-07-22)
Previous findings indicate that vitamin K2 (menaquinone) may play a role in controlling cell growth. To determine whether vitamin K2 has preventive effects on the development of hepatocellular carcinoma in women with viral cirrhosis of the liver. Forty women diagnosed
H H Thijssen et al.
The British journal of nutrition, 75(1), 121-127 (1996-01-01)
We measured the vitamin K status in postmortem human tissues (brain, heart, kidney, liver, lung, pancreas) to see if there is a tissue-specific distribution pattern. Phylloquinone (K1) was recovered in all tissues with relatively high levels in liver, heart and
Kerry Routenberg Love et al.
Nature chemical biology, 3(11), 697-705 (2007-10-20)
The addition of ubiquitin (Ub) and ubiquitin-like (Ubl) modifiers to proteins serves to modulate function and is a key step in protein degradation, epigenetic modification and intracellular localization. Deubiquitinating enzymes and Ubl-specific proteases, the proteins responsible for the removal of
F Jerry Reen et al.
PloS one, 8(1), e54479-e54479 (2013-02-06)
LysR-type transcriptional regulators (LTTRs) are emerging as key circuit components in regulating microbial stress responses and are implicated in modulating oxidative stress in the human opportunistic pathogen Pseudomonas aeruginosa. The oxidative stress response encapsulates several strategies to overcome the deleterious
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实验方案

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

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