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Merck
CN

47775

甲萘醌 (K3)

analytical standard

别名:

甲萘醌, 2-甲基-1,4-萘醌, 维生素 K3

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关于此项目

经验公式（希尔记法）:
C11H8O2
化学文摘社编号:
58-27-5
分子量:
172.18
EC Number:
200-372-6
UNSPSC Code:
12164500
PubChem Substance ID:
24871411
Beilstein/REAXYS Number:
1908453
MDL number:
MFCD00001681
NACRES:
NA.24

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InChI key

MJVAVZPDRWSRRC-UHFFFAOYSA-N

InChI

1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3

SMILES string

CC1=CC(=O)c2ccccc2C1=O

grade

analytical standard

CofA

current certificate can be downloaded

feature

standard type fat soluble vitamin

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

105-107 °C (lit.)

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-30°C

Quality Level

100

Gene Information

human ... NQO1(1728)

相关类别

General description

甲萘醌是一种促血栓形成的化合物，属于维生素K类化合物，其对于凝血酶原和其他凝血因子的生物合成是必不可少的。它可用作细胞培养和体内研究中的模型醌。 它是叶绿醌的分解代谢产物，是大鼠组织中甲萘醌4的循环前体。
甲萘醌（K3）是一种脂溶性维生素前体，它是肠中口服叶绿醌（维生素k1）的分解代谢产物。

Application

有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。
甲萘醌（K3）可用作液相色谱技术定量测定生物体液中分析物的分析参考标准品。

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
LRAE0435
LRAD2358
LRAC4189
LC22078V
LC21552V

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Development of a validated liquid chromatography method for the simultaneous determination of eight fat-soluble vitamins in biological fluids after solid-phase extraction
Chatzimichalakis FP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 805(2), 289-296 (2004)
Arne Søraas et al.
Journal of oral microbiology, 6 (2014-09-11)
The prevalence of infections caused by Cefotaximase-Munich (CTX-M)-type extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has rapidly increased during the past 15 years. Enterobacteriaceae are commonly found in the gastrointestinal tract and long-term intestinal carriage is considered important for the spread of ESBL
Kerry Routenberg Love et al.
Nature chemical biology, 3(11), 697-705 (2007-10-20)
The addition of ubiquitin (Ub) and ubiquitin-like (Ubl) modifiers to proteins serves to modulate function and is a key step in protein degradation, epigenetic modification and intracellular localization. Deubiquitinating enzymes and Ubl-specific proteases, the proteins responsible for the removal of
H H Thijssen et al.
The British journal of nutrition, 75(1), 121-127 (1996-01-01)
We measured the vitamin K status in postmortem human tissues (brain, heart, kidney, liver, lung, pancreas) to see if there is a tissue-specific distribution pattern. Phylloquinone (K1) was recovered in all tissues with relatively high levels in liver, heart and
Daiki Habu et al.
JAMA, 292(3), 358-361 (2004-07-22)
Previous findings indicate that vitamin K2 (menaquinone) may play a role in controlling cell growth. To determine whether vitamin K2 has preventive effects on the development of hepatocellular carcinoma in women with viral cirrhosis of the liver. Forty women diagnosed
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实验方案

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

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