442388
3-甲基胆蒽
analytical standard
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关于此项目
经验公式（希尔记法）:
C21H16
化学文摘社编号:
分子量:
268.35
EC Number:
200-276-4
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1913890
MDL number:
NACRES:
NA.24
产品名称
3-甲基胆蒽, analytical standard
InChI key
PPQNQXQZIWHJRB-UHFFFAOYSA-N
InChI
1S/C21H16/c1-13-6-7-15-12-20-17-5-3-2-4-14(17)8-9-18(20)19-11-10-16(13)21(15)19/h2-9,12H,10-11H2,1H3
SMILES string
Cc1ccc2cc3c(ccc4ccccc34)c5CCc1c25
grade
analytical standard
CofA
current certificate can be downloaded
packaging
ampule of 50 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
bp
280 °C/80 mmHg (lit.)
mp
178-180 °C (lit.)
application(s)
environmental
format
neat
storage temp.
2-30°C
Quality Level
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Application
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
General description
3-甲基胆蒽，一种有效的多环芳烃受体激动剂，是一种致癌物，可作为各种有机物质（如煤、垃圾、气和油）燃烧的副产物获得。抑制人脐静脉内皮细胞的增殖。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Molecular mechanisms of p21 and p27 induction by 3?methylcholanthrene, an aryl?hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells
Pang P-H, et al.
Journal of Cellular Physiology, 215, 161-171 (2008)
Attenuation of polycyclic aromatic hydrocarbon (PAH)-mediated pulmonary carcinogenesis in mice by omega-3-fatty acids
Moorthy B, et al.
Faseb Journal, 31, 1067-1064 (2017)
Mechanism of p53-dependent apoptosis induced by 3-methylcholanthrene involvement of p53 phosphorylation and p38 MAPK
Kwon YW, et al.
The Journal of Biological Chemistry, 277, 1837-1844 (2002)
3?Methylcholanthrene/Aryl?Hydrocarbon Receptor?Mediated Hypertension Through eNOS Inactivation
Chang C-C, et al.
Journal of Cellular Physiology, 232, 1020-1029 (2017)
Elin Swedenborg et al.
Molecular and cellular endocrinology, 362(1-2), 39-47 (2012-05-29)
The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (EDCs), compounds that interfere with hormonal signaling. 3-Methylcholanthrene (3-MC) and dioxin (TCDD) are EDCs and prototypical aryl hydrocarbon receptor
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