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等级
analytical standard
质量水平
CofA
current certificate can be downloaded
包装
ampule of 50 mg
技术
HPLC: suitable
gas chromatography (GC): suitable
沸点
280 °C/80 mmHg (lit.)
mp
178-180 °C (lit.)
应用
environmental
包装形式
neat
储存温度
2-30°C
SMILES字符串
Cc1ccc2cc3c(ccc4ccccc34)c5CCc1c25
InChI
1S/C21H16/c1-13-6-7-15-12-20-17-5-3-2-4-14(17)8-9-18(20)19-11-10-16(13)21(15)19/h2-9,12H,10-11H2,1H3
InChI key
PPQNQXQZIWHJRB-UHFFFAOYSA-N
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相关类别
一般描述
3-甲基胆蒽，一种有效的多环芳烃受体激动剂，是一种致癌物，可作为各种有机物质（如煤、垃圾、气和油）燃烧的副产物获得。抑制人脐静脉内皮细胞的增殖。
应用
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
警示用语：
Danger
危险声明
危险分类
Aquatic Chronic 4 - Carc. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Mechanism of p53-dependent apoptosis induced by 3-methylcholanthrene involvement of p53 phosphorylation and p38 MAPK
Kwon YW, et al.
The Journal of Biological Chemistry, 277, 1837-1844 (2002)
Attenuation of polycyclic aromatic hydrocarbon (PAH)-mediated pulmonary carcinogenesis in mice by omega-3-fatty acids
Moorthy B, et al.
Faseb Journal, 31, 1067-1064 (2017)
Molecular mechanisms of p21 and p27 induction by 3?methylcholanthrene, an aryl?hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells
Pang P-H, et al.
Journal of Cellular Physiology, 215, 161-171 (2008)
3?Methylcholanthrene/Aryl?Hydrocarbon Receptor?Mediated Hypertension Through eNOS Inactivation
Chang C-C, et al.
Journal of Cellular Physiology, 232, 1020-1029 (2017)
Elin Swedenborg et al.
Molecular and cellular endocrinology, 362(1-2), 39-47 (2012-05-29)
The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (EDCs), compounds that interfere with hormonal signaling. 3-Methylcholanthrene (3-MC) and dioxin (TCDD) are EDCs and prototypical aryl hydrocarbon receptor
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