推荐产品
产品名称
Astec® CYCLOBOND I 2000 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 2.1 mm
物料
stainless steel column
质量水平
产品线
Astec®
包装
pkg of 1 ea
制造商/商品名称
Astec®
参数
0-50 °C temperature
172 bar pressure (2500 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
15 cm × 2.1 mm
基质
silica particle platform
基质活性基团
cyclodextrin, beta- phase
粒径
5 μm
孔径
100 Å
工作pH值
3.5-7
分离技术
chiral
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一般描述
CYCLOBOND I 2000 通过一个有专利的工艺与 β-环糊精结合，生成稳定的基质，环糊精的排列方式使其保留了形成包合物的最有价值的性质。这允许它们通过选择性地将多种有机分子包括在其空腔中，来实现多种化学分离。对于各种分子类型，极性有机模式也可以进行非包含型分离。
资源：
CYCLOBOND 常见问题解答
CYCLOBOND参考文献
手性产品文献
- 结合阶段：未衍生化的、天然的 β-环糊精
资源：
CYCLOBOND 常见问题解答
CYCLOBOND参考文献
手性产品文献
应用
- Thioether bridged cationic cyclodextrin stationary phases: Effect of spacer length, selector concentration and rim functionalities on the enantioseparation.: This study investigates the effect of different variables on the enantioseparation efficiency of thioether bridged cationic cyclodextrin stationary phases, utilizing the Astec CYCLOBOND 2000 Chiral HPLC Column for the separation processes (Li et al., 2016).
- Enantiomeric separations of illicit drugs and controlled substances using cyclofructan-based (LARIHC) and cyclobond I 2000 RSP HPLC chiral stationary phases.: This research explores the use of cyclobond I 2000 RSP HPLC chiral stationary phases, including Astec CYCLOBOND 2000, in the enantiomeric separation of various illicit drugs and controlled substances (Padivitage et al., 2014).
- Screening approach, optimisation and scale-up for chiral liquid chromatography of cathinones.: The paper discusses a screening approach and optimization methods for chiral liquid chromatography of cathinones, highlighting the application of Astec CYCLOBOND 2000 Chiral HPLC Column in these processes (Perera et al., 2012).
- Stereoselective analysis of hydroxybupropion and application to drug interaction studies.: This study focuses on the stereoselective analysis of hydroxybupropion using chiral stationary phases, including Astec CYCLOBOND 2000, to explore drug interaction effects (Xu et al., 2007).
- Solid-phase extraction of methadone enantiomers and benzodiazepines in biological fluids by two polymeric cartridges for liquid chromatographic analysis.: This research investigates the extraction and analysis of methadone enantiomers and benzodiazepines in biological fluids using the Astec CYCLOBOND 2000 Chiral HPLC Column for effective separation (He et al., 2005).
法律信息
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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Liquid chromatographic resolution of enantiomers of deltahedral carborane and metallaborane derivatives
Plesek, Jaromir, et al.
Journal of Chromatography A, 626 (2), 197-206 (1992)
Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with high-performance liquid chromatography and capillary zone electrophoresis
Schuster, Andreas, et al.
Journal of Chromatography A, 793 (1), 77-90 (1998)
High-performance liquid chromatography of diastereomeric flavanone glycosides in Citrus on a ?-cyclodextrin-bonded stationary phase (Cyclobond I)
Krause, Martin; Galensa, Rudolf
Journal of Chromatography A, 588 (1-2), 41-45 (1991)
Chiral separations of ?-blocking drug substances using chiral stationary phases
Ekelund, Jens, et al.
Journal of Chromatography A, 708 (2), 253-261 (1995)
A F Casy et al.
Journal of pharmaceutical and biomedical analysis, 9(10-12), 787-792 (1991-01-01)
The interaction of beta-cyclodextrin with a series of structurally related chiral thromboxane antagonists was investigated using NMR and RP-HPLC. HPLC studies used both a cyclodextrin bonded phase (Cyclobond I), and beta-cyclodextrin as a mobile phase additive with an achiral C8
商品
Read our Biofiles article on Analysis of Isoprenoid Pathway Metabolites by LC-MS.
相关内容
CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.
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