产品名称
Astec® CHIROBIOTIC® V2手性HPLC色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
agency
suitable for USP L88
description
HPLC column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature
241 bar pressure (3500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
15 cm × 4.6 mm
matrix
High-purity silica gel particle platform
fully porous particle
matrix active group
vancomycin phase
particle size
5 μm
pore size
200 Å
operating pH range
3.5-7.0
separation technique
chiral
Quality Level
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Application
- Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma and its application to pharmacokinetic study.：研究表明Astec® CHIROBIOTIC® V2手性HPLC色谱柱在药动学研究中可用于准确的对映选择性分析，特别是精神活性成分。柱子可有效分离和定量血浆中的手性药物及其代谢物，提供有价值的药物开发和治疗监测信息(Zhang et al., 2016)。
- New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.：采用Astec® CHIROBIOTIC® V2手性HPLC色谱柱手性分离华法林对映异构体。提供抗凝药物分析的稳健工具，有助药动学评估和用药剂量优化(Malakova et al., 2009)。
General description
- 键合相：万古霉素
- 工作pH范围：3.5 - 7.0
- 粒径：5、10或16 μm
- 孔径：100Å（CHIROBIOTIC® V）或200Å（CHIROBIOTIC® V2）
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
Legal Information
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
实验方案
In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.
Optimized sample prep and chiral chromatography methods for the LC/MS analysis of these drug enantiomers in urine
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