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14022AST

Supelco

Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns

L × I.D. 10 cm × 4.6 mm, HPLC Column

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UNSPSC代码:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec® CHIROBIOTIC® TAG 手性 HPLC色谱 柱, 5 μm particle size, L × I.D. 10 cm × 4.6 mm

物料

stainless steel column

质量水平

Agency

suitable for USP L63

描述

HPLC column

产品线

Astec®

包装

pkg of 1 ea

制造商/商品名称

Astec®

参数

0-45 °C temperature
241 bar pressure (3500 psi)

技术

HPLC: suitable
LC/MS: suitable

长度 × 内径

10 cm × 4.6 mm

基质

High-purity silica gel particle platform
fully porous particle

基质活性基团

teicoplanin aglycone phase

粒径

5 μm

孔径

100 Å

operating pH range

3.0-6.8

分离技术

chiral

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相关类别

一般描述

去掉三个碳水化合物单体后,CHIROBIOTIC®TAG便有了CHIROBIOTIC®T互补选择性。对于许多氨基酸,α, β, γ环状,尤其是含有硫的蛋氨酸、组氨酸和半胱氨酸的分辨度增高。对于一些中性分子,比如恶唑烷酮、乙内酰脲类和二氮嗪,分辨度也增强了,尤其在单溶剂甲醇、乙醇和乙腈中效果显著。一些酸性分子选择性也增强了

  • 连接相:替考拉宁苷元
  • pH适用范围:3.0 - 6.8
  • 粒子直径:5, 10或16 μm
  • 孔径:100 Å

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法律信息

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

法规信息

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Julia Koidl et al.
Journal of biochemical and biophysical methods, 70(6), 1254-1260 (2007-11-06)
This paper deals with the chiral separation of triiodothyronine (T3) and thyroxine (T4) by HPLC and micro-HPLC. The separation of T3 and T4 is of great pharmaceutical and clinical interest, since the enantiomers exhibit different pharmacological activities. The HPLC measurements
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea, Paula Veronica, et al.
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)
Ilaria D'Acquarica et al.
Journal of chromatography. A, 1061(2), 167-173 (2005-01-12)
We describe a new tandem-columns chiral-achiral HPLC arrangement by using a chiral column (CHIROBIOTIC TAG) connected in series with an achiral column (Spherisorb S5 SCX), based on a strong cationic exchange mechanism; this approach is very useful for the analysis
Markus Fuereder et al.
Journal of chromatography. A, 1236, 123-131 (2012-04-03)
Teicoplanin aglycone-based chromatography columns (Chirobiotic TAG) enable amino acid enantioseparation with aqueous mobile phases, which perfectly accommodates the distinct hydrophilicity of most amino acids. Therefore, this stationary phase constitutes a promising option in particular for preparative-scale separations that require high
Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary

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