推荐产品
产品名称
Astec® CHIROBIOTIC® V 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 10 mm
物料
stainless steel column
Agency
suitable for USP L88
描述
HPLC Column
产品线
Astec®
包装
pkg of 1 ea
制造商/商品名称
Astec®
参数
0-45 °C temperature
241 bar pressure (3500 psi)
技术
HPLC: suitable
LC/MS: suitable
长度 × 内径
25 cm × 10 mm
基质
High-purity silica gel particle platform
fully porous particle
基质活性基团
vancomycin phase
粒径
5 μm
孔径
100 Å
工作pH值
3.5-7.0
分离技术
chiral
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一般描述
中性分子、酰胺、酸、酯和胺对这些基于万古霉素的CSP具有相当大的对映选择性。在极性离子模式下,在CHIROBIOTIC® V上可分离多种仲胺和叔胺。CHIROBIOTIC® V已被证明具有许多蛋白质固定相的分离特性,但又具有优异的稳定性和更高的样品容量。部分尚无采用其他手性固定相分离报道的手性分析物也已在其上得到分离。CHIROBIOTIC® V和V2的成键化学特性不同,载体颗粒的孔径不同,因而各自具有不同的灵敏度和制备能力。
- 键合相:万古霉素
- 工作pH范围: 3.5 - 7.0
- 粒径:5、10或16 μm
- 孔径:100 Å (CHIROBIOTIC® V)或200 Å (CHIROBIOTIC® V2)
法律信息
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
法规信息
新产品
J P Bagnall et al.
Journal of chromatography. A, 1249, 115-129 (2012-07-04)
This paper presents and compares for the first time two chiral LC-QTOF-MS methodologies (utilising CBH and Chirobiotic V columns with cellobiohydrolase and vancomycin as chiral selectors) for the quantification of amphetamine, methamphetamine, MDA (methylenedioxyamphetamine), MDMA (methylenedioxymethamphetamine), propranolol, atenolol, metoprolol, fluoxetine
Analysis of the enantiomers of citalopram and its demethylated metabolites using chiral liquid chromatography
Kosel, M., et al.
Journal of Chromatography. B, Biomedical Applications, 719 (1-2), 234-238 (1998)
HPLC separation technique for analysis of bufuralol enantiomers in plasma and pharmaceutical formulations using a vancomycin chiral stationary phase and UV detection
Hefnawy, Mohamed M., et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 856 (1-2), 328-336 (2007)
Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series
Rao, R. Nageswara, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879 (21), 1911-1916 (2011)
Chiral stability-indicating HPLC method for analysis of arotinolol in pharmaceutical formulation and human plasma
Sultan, Maha A., et al.
Arabian Journal of Chemistry, 3 (3), 147-153 (2010)
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