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产品线
Carboxen®
表单
powder
包装
bottle of 10 g
技术
LPLC: suitable
表面积
~485 m2/g
基质
Carboxen® 569
基质活性基团
carbon
粒径
20-45 mesh
孔径
~0.10 cm3/g macroporosity
~0.14 cm3/g mesoporosity
~0.20 cm3/g microporosity
~5-8 Å pore diameter
密度
~0.61 g/mL (free fall density)
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一般描述
Carboxen是由高分子前体高度改性而成的人造碳吸附剂。这种粒子既不会像树脂一样发生塑性变形,也不会像活性炭一样产生细微颗粒。以干燥形式储运。Carboxen作为衍生树脂适合各种去除小分子和大分子杂质的纯化应用。气相和液相纯化皆可。包括,去除原料药(API)中的均相催化剂,在生化纯化中去除高风险杂质(如,单抗中的残留宿主细胞蛋白),去除重金属,纯化氯化物,去除可萃取物和可浸出物。大小不一的渐变孔径改善了吸附和解吸的热力学和动力学特性。Carboxen形式多样,具有不同的孔结构(微孔、中孔和大孔比例不同)、比表面积和表面pH。
特点和优势
特点及优势:
- 球形
- 坚硬,球盘硬度>98%
- 温度稳定性高达400°C
- 高纯度
- 易于填料
- 全pH范围下稳定
- 不产生背压
- 渗透压冲击稳定性高
- 渐变式孔径(从大孔到中孔再到微孔)
其他说明
有关更多信息,请访问:特种碳吸附剂
法律信息
Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
4.1B - Flammable solid hazardous materials
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
RSC Chromatography Monographs
Pawliszyn J. et al.
Applications of Solid Phase Microextraction, 64-65 (1999)
Evaluation of Carboxen carbon molecular sieves for trapping replacement chlorofluorocarbons.
O'Doherty SJ, et al.
Journal of Chromatography A, 630 (1), 265-274 (1993)
Filippo Maggi et al.
Chemistry & biodiversity, 8(1), 95-114 (2011-01-25)
Headspace solid-phase microextraction (HS-SPME) coupled with GC/FID and GC/MS was applied for the first time in the analysis of the volatile fraction of an Ephedra species. Notably, six Italian populations (Marche, Abruzzo, and Sardinia) of Ephedra nebrodensis subsp. nebrodensis, covering
Frank Sporkert et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 772(1), 45-51 (2002-05-23)
A new and in part automated headspace solid-phase microextraction method for quantitative determination of the highly toxic rodenticide fluoroacetic acid (FAA) in serum and other biological samples has been developed. FAA and deuterated acetic acid (internal standard) were extracted from
Jacek A Koziel et al.
Journal of the Air & Waste Management Association (1995), 55(8), 1147-1157 (2005-09-29)
Odorous gases associated with livestock operations are complex mixtures of hundreds if not thousands of compounds. Research is needed to know how best to sample and analyze these compounds. The main objective of this research was to compare recoveries of
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