产品线
Carboxen®
质量水平
形式
powder
包装
bottle of 10 g
技术
LPLC: suitable
表面积
~485 m2/g
基质
Carboxen® 569
基质活性基团
carbon
粒径
20-45 mesh
孔径
~0.10 cm3/g macroporosity
~0.14 cm3/g mesoporosity
~0.20 cm3/g microporosity
~5-8 Å pore diameter
密度
~0.61 g/mL (free fall density)
分离技术
reversed phase
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一般描述
Carboxen是由高分子前体高度改性而成的人造碳吸附剂。这种粒子既不会像树脂一样发生塑性变形，也不会像活性炭一样产生细微颗粒。以干燥形式储运。Carboxen作为衍生树脂适合各种去除小分子和大分子杂质的纯化应用。气相和液相纯化皆可。包括，去除原料药(API)中的均相催化剂，在生化纯化中去除高风险杂质（如，单抗中的残留宿主细胞蛋白），去除重金属，纯化氯化物，去除可萃取物和可浸出物。大小不一的渐变孔径改善了吸附和解吸的热力学和动力学特性。Carboxen形式多样，具有不同的孔结构（微孔、中孔和大孔比例不同）、比表面积和表面pH。
特点和优势
特点及优势：
- 球形
- 坚硬，球盘硬度>98%
- 温度稳定性高达400°C
- 高纯度
- 易于填料
- 全pH范围下稳定
- 不产生背压
- 渗透压冲击稳定性高
- 渐变式孔径（从大孔到中孔再到微孔)
其他说明
有关更多信息，请访问：特种碳吸附剂
法律信息
Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
4.1B - Flammable solid hazardous materials
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
RSC Chromatography Monographs
Pawliszyn J. et al.
Applications of Solid Phase Microextraction, 64-65 (1999)
Evaluation of Carboxen carbon molecular sieves for trapping replacement chlorofluorocarbons.
O'Doherty SJ, et al.
Journal of Chromatography A, 630 (1), 265-274 (1993)
B D Page et al.
Journal of chromatography. A, 873(1), 79-94 (2000-04-11)
The headspace solid-phase microextraction (HS-SPME) efficiencies from vegetable oil of the recently available Carboxen-poly(dimethylsiloxane) (PDMS) and divinylbenzene-Carboxen-PDMS fibres were found to be much greater than those of the PDMS fibre for a number of volatile contaminants. Using these Carboxen-based fibres
Dawn M Chapman et al.
Journal of agricultural and food chemistry, 52(17), 5431-5435 (2004-08-19)
A rapid and automated solid phase microextraction (SPME) stable isotope dilution gas chromatography/mass spectrometry (GC-MS) method for 2-methoxy-3-isobutylpyrazine (MIBP) quantification in red wine was developed. Wines with 30% (w/v) NaCl and 2-methoxy-(2)H(3)-3-isobutylpyrazine internal standard were sampled with a 2 cm
Lucia Giordano et al.
Journal of chromatography. A, 1017(1-2), 141-149 (2003-10-31)
A new method was developed for the determination of 2-furfural (2-F) and 5-methylfurfural (5-MF), two products of Maillard reaction in vinegar, with head-space solid-phase microextraction (HS-SPME) coupled to gas chromatography-mass spectrometry (GC-MS). A divinylbenzene (DVB)/carboxen (CAR)/polydimethylsiloxane (PDMS) fibre was used
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