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安全信息

Z4777

Sigma-Aldrich

ZK 200775 hydrate

≥98% (HPLC), powder

别名:

Fanapanel, MPQX, [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-phosphonic acid hydrate

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About This Item

经验公式（希尔记法）:
C14H15F3N3O6P · xH2O
CAS号:
1255517-78-2
分子量:
409.25 (anhydrous basis)
MDL编号:
MFCD18452859
UNSPSC代码:
12352200
PubChem化学物质编号:
329831618
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

颜色

off-white to light brown

溶解性

DMSO: ≥20 mg/mL

储存温度

2-8°C

SMILES字符串

O.OP(O)(=O)CN1C(=O)C(=O)Nc2cc(c(cc12)N3CCOCC3)C(F)(F)F

InChI

1S/C14H15F3N3O6P.H2O/c15-14(16,17)8-5-9-11(6-10(8)19-1-3-26-4-2-19)20(7-27(23,24)25)13(22)12(21)18-9;/h5-6H,1-4,7H2,(H,18,21)(H2,23,24,25);1H2

InChI key

RYQLMFHPDNKPKY-UHFFFAOYSA-N

比较类似商品

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1 of 4

此商品
F3917D3658F6886
6-乙酰-7-脱乙酰福斯考灵 ≥95% (HPLC)

SML2801

6-乙酰-7-脱乙酰福斯考灵

毛喉素 For use in molecular biology applications

F3917

毛喉素

1,9-Dideoxyforskolin from Coleus forskohlii ≥97%, solid

D3658

1,9-Dideoxyforskolin from Coleus forskohlii

毛喉素 from Coleus forskohlii, ≥98% (HPLC), powder

F6886

毛喉素

form

powder

form

powder

form

solid

form

powder

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

-

solubility

DMF:H2O (9:1): 2 mg/mL, clear

solubility

ethanol: soluble

solubility

methanol: 28 mg/mL(lit.), DMSO: 3 mg/mL(lit.), chloroform: 50 mg/mL, ethanol: 6.6 mg/mL(lit.), dilute aqueous acid and base: insoluble(lit.)

solubility

ethanol: soluble 50 mg/mL

color

white to beige

color

white to off-white

color

white to off-white

color

white to off-white

一般描述

Z 200775 is a competetive AMPA/kainate receptor antagonist.
ZK 200775 is a selective AMPA/kainite receptor antagonist with very low affinity for NMDA associated binding sites (Ki for CNQX binding site = 32 nM vs. 2.8 uM for DCKA binding site.) ZK 200775 displays superior PK and safety profiles in in vivo studies compared to quinoxalinedione antagonists such as NBQX, showing no effects on motor behavior or cardiac events at efficacious doses in rat. Additionally, unlike other quinoxalinediones, ZK 200775 is water soluble, making this a desirable tool compound for in vivo studies.

特点和优势

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    110M4602V
    0000070377
    110M4602V
    0000070377
    110M4602

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