Z4402
Zinterol hydrochloride
≥98% (HPLC)
别名:
Zinterol hydrochloride, N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]-Methanesulfonamide Hydrochloride; MJ 9184
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所有图片(1)
About This Item
经验公式（希尔记法）:
C19H26N2O4S·HCl
CAS号:
分子量:
414.95
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
检测方案
≥98% (HPLC)
形式
powder
储存条件
desiccated
溶解性
DMSO: ≥15 mg/mL
储存温度
room temp
SMILES字符串
CC(C)(Cc1ccccc1)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2
InChI
1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3
InChI key
XJBCFFLVLOPYBV-UHFFFAOYSA-N
生化/生理作用
Zinterol Hydrochloride is a β2 adrenergic receptor selective agonist.
特点和优势
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Ismayil Ahmet et al.
Circulation, 110(9), 1083-1090 (2004-08-18)
Studies in isolated cardiac myocytes have demonstrated that signaling via specific beta1-adrenergic receptor subtypes (beta1ARs) promotes but that signaling via beta2ARs protects from cell death. We hypothesized that prolonged beta(2)AR stimulation or beta1AR blockade would each protect myocytes from death
George E Billman et al.
American journal of physiology. Heart and circulatory physiology, 290(6), H2590-H2599 (2006-01-03)
Enhanced cardiac beta(2)-adrenoceptor (beta(2)-AR) responsiveness can increase susceptibility to ventricular fibrillation (VF). Exercise training can decrease cardiac sympathetic activity and could, thereby, reduce beta(2)-AR responsiveness and decrease the risk for VF. Therefore, dogs with healed myocardial infarctions were subjected to
Susan F Steinberg et al.
American journal of physiology. Heart and circulatory physiology, 282(4), H1181-H1188 (2002-03-15)
We studied the role of beta-adrenergic receptor subtype signaling to cAMP and calcium in the genesis of catecholamine-dependent arrhythmias in German shepherd dogs that develop lethal arrhythmias at ~5 mo of age. There were three major findings in this study:
H E Lara et al.
Endocrine, 15(2), 187-192 (2001-11-27)
We investigated the possibility that norepinephrine from the human ovary is released after nerve stimulation and that this neurotransmitter is coupled to a steroidogenic response. Biologically significant levels of both norepinephrine and dopamine were found in human ovarian biopsies. [3H]norepinephrine
Dana S Hutchinson et al.
Naunyn-Schmiedeberg's archives of pharmacology, 373(2), 158-168 (2006-04-08)
The present study investigates the action of zinterol at beta(3)-adrenoceptors. We used mouse primary brown adipocytes and Chinese hamster ovary (CHO-K1) cells expressing the mouse or human beta(3)-adrenoceptor. Zinterol was a full agonist at increasing cyclic AMP levels in primary
商品
β-肾上腺素受体可被去甲肾上腺素或肾上腺素激活。详细了解β-肾上腺素受体在蛋白质表达、细胞信号传导和代谢研究中的作用。
β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.
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