Z0417
β-玉米赤霉醇
~98% (HPLC), nonsteroidal estrogen, powder
别名:
2,4-二羟基-6-（6β1,10-二羟基十一基 ] 苯甲酸 μ-内酯
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关于此项目
经验公式（希尔记法）:
C18H26O5
化学文摘社编号:
分子量:
322.40
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
β-玉米赤霉醇, ~98% (HPLC)
SMILES string
C[C@H]1CCC[C@@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1
InChI
1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14-/m0/s1
InChI key
DWTTZBARDOXEAM-JSGCOSHPSA-N
sterility
non-sterile
assay
~98% (HPLC)
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
availability
not available in Canada
solubility
methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
rat ... Ar(24208)
signalword
Danger
hcodes
Hazard Classifications
Repr. 2 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
涉药品监管产品
此项目有
Erika Pfeiffer et al.
Molecular nutrition & food research, 54(10), 1468-1476 (2010-04-17)
Glucuronidation constitutes an important pathway in the phase II metabolism of the mycotoxin zearalenone (ZEN) and the growth promotor α-zearalanol (α-ZAL, zeranol), but the enzymology of their formation is yet unknown. In the present study, ZEN, α-ZAL and four of
B H Migdalof et al.
Xenobiotica; the fate of foreign compounds in biological systems, 13(4), 209-221 (1983-04-01)
The disposition of [3H]zeranol has been studied in the female Wistar rat, New Zealand rabbit, beagle dog, rhesus monkey and man. The blood elimination half-life of total radioactivity in rabbit was 26 h, monkey 18 h and man 22 h.
H Malekinejad et al.
Veterinary research communications, 30(4), 445-453 (2006-02-28)
The enzymes 3alpha- and 3beta-hydroxysteroid dehydrogenase (3alpha- and 3beta-HSD) play a pivotal role in synthesis of various steroid hormones including oestradiol and testosterone. The structure of the mycotoxin zearalenone resembles many characteristics of steroids and binds to oestrogen receptors as
Zearalenones: characterization of the estrogenic potencies and receptor interactions of a series of fungal beta-resorcylic acid lactones.
B S Katzenellenbogen et al.
Endocrinology, 105(1), 33-40 (1979-07-01)
D J Everett et al.
Journal of toxicology and environmental health, 20(4), 435-443 (1987-01-01)
Uterotrophic response in sexually immature female rats has been used to rank the relative estrogenic potencies of six resorcylic acid lactones (RALs) and to compare their activities with that of 17 beta-estradiol. On oral administration, the estrogenic potency relative to
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