Z0153
ZM 241385
≥98% (HPLC), adenosine A2A antagonist, powder
别名:
4-(-2-[7-氨基-2-{2-呋喃基}{1,2,4}三唑并{2,3-a}{1,3,5}三嗪-5-基-氨基]乙基)苯酚
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关于此项目
经验公式（希尔记法）:
C16H15N7O2
化学文摘社编号:
分子量:
337.34
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
ZM 241385, ≥98% (HPLC)
SMILES string
Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4
InChI key
PWTBZOIUWZOPFT-UHFFFAOYSA-N
InChI
1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)
assay
≥98% (HPLC)
form
powder
color
white to tan
solubility
DMSO: >15 mg/mL
storage temp.
room temp
Quality Level
相关类别
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Sergey Ryzhov et al.
Journal of the American Heart Association, 8(13), e010874-e010874 (2019-06-27)
Background Patients resuscitated from cardiac arrest ( CA ) have highly variable neurological, circulatory, and systemic ischemia-reperfusion injuries. After the initial hypoxic-ischemic insult, a cascade of immune and inflammatory responses develops and is often fatal. The role of the immune
Fabrizio Vincenzi et al.
PloS one, 7(6), e39317-e39317 (2012-07-05)
A(3) adenosine receptors (ARs) play a pivotal role in the development of cancer and their activation is involved in the inhibition of tumor growth. The effects of pulsed electromagnetic fields (PEMFs) on cancer have been controversially discussed and the detailed
Tarek K Motawi et al.
Molecular and cellular biochemistry, 465(1-2), 89-102 (2019-12-11)
Parkinson's disease (PD) is the second common age-related neurodegenerative disease. It is characterized by control loss of voluntary movements control, resting tremor, postural instability, bradykinesia, and rigidity. The aim of the present work is to evaluate curcumin, niacin, dopaminergic and
Chiara Zoppellaro et al.
PloS one, 8(8), e72648-e72648 (2013-09-10)
Adenosine plays an important role in regulating intestinal motility and inflammatory processes. Previous studies in rodent models have demonstrated that adenosine metabolism and signalling are altered during chronic intestinal inflammatory diseases. However, the involvement of the adenosinergic system in the
William H Wheat et al.
Stem cells and development, 26(4), 249-262 (2016-11-16)
Mesenchymal stem cells (MSC) represent a readily accessible source of cells with potent immune modulatory activity. MSC can suppress ongoing inflammatory responses by suppressing T cell function, while fewer studies have examined the impact of MSC on dendritic cell (DC)
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