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Merck
CN

X6000

丁苄唑啉 盐酸盐

别名:

2-(4--丁基-2,6-二甲基苄基)-2-咪唑啉 盐酸盐

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关于此项目

经验公式(希尔记法):
C16H24N2 · HCl
化学文摘社编号:
分子量:
280.84
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
214-936-4
MDL number:
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InChI key

YGWFCQYETHJKNX-UHFFFAOYSA-N

InChI

1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H

SMILES string

CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl

originator

Novartis

Quality Level

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Biochem/physiol Actions

α-肾上腺素能受体激动剂;咪唑啉结合位点配体。

Features and Benefits

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单,请单击此处

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Britta Haenisch et al.
Fundamental & clinical pharmacology, 24(6), 729-739 (2009-12-25)
Oxymetazoline and xylometazoline are both used as nasal mucosa decongesting α-adrenoceptor agonists during a common cold. However, it is largely unknown which of the six α-adrenoceptor subtypes are actually present in human nasal mucosa, which are activated by the two
Görkem Eskiizmir et al.
European journal of clinical pharmacology, 67(1), 19-23 (2010-11-12)
Oxymetazoline and xylometazoline are locally effective and direct acting drugs that relieve nasal congestion. The aim of this study was to objectively determine and compare the decongestive effects of oxymetazoline and xylometazoline in healthy subjects. The study population comprised thirty
I T Bognar et al.
The Journal of pharmacology and experimental therapeutics, 254(2), 702-710 (1990-08-01)
Rat hearts were isolated with the vagus nerves intact and perfused, and the neuronal acetylcholine stores were pulse labeled with [14C]choline. The overflow of [14C]choline/acetylcholine evoked by extrinsic vagus nerve stimulation (3 Hz and 720 pulses or 10 Hz and
Helle L Thulesius et al.
Rhinology, 49(1), 46-52 (2011-04-07)
Rhinomanometry before and after decongestion distinguishes a nasal airway organic stenosis from congestion of nasal mucosa in patients with nasal stuffiness. Together with rhinoscopy and patient history, it is used to decide if nasal surgery would benefit the patient. Rhinomanometry
Katarzyna Korzeniowska et al.
Przeglad lekarski, 69(10), 1168-1169 (2013-02-21)
The article describes the case of 34-years old man, who has used nasal drops with xylomethazoline for three years. Health consequence of uncontrolled use of the drops and treatment were prescribed. Described problem confirms the need of physicians and pharmacists

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