X4002
黄嘌呤
≥99%, synthetic (organic), powder
别名:
2,6-二羟基嘌呤
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关于此项目
经验公式（希尔记法）:
C5H4N4O2
化学文摘社编号:
分子量:
152.11
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-718-6
MDL number:
Beilstein/REAXYS Number:
8733
产品名称
黄嘌呤, BioUltra, ≥99%
InChI key
LRFVTYWOQMYALW-UHFFFAOYSA-N
InChI
1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
SMILES string
O=C1NC(=O)c2nc[nH]c2N1
biological source
synthetic (organic)
product line
BioUltra
assay
≥99%
form
powder
impurities
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
ign. residue
≤0.1%
solubility
1 M NaOH: 0.1 M, clear, colorless to light yellow
anion traces
sulfate (SO42-): <0.05%
cation traces
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%
Quality Level
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Application
本品（黄嘌呤）可作为底物测定黄嘌呤氧化酶(XOD)的抑制性。还可用于：
- 酵母培养
- 人类细胞系培养
- 重组病毒克隆为大肠杆菌中的BAC(细菌人工染色体)
Biochem/physiol Actions
黄嘌呤和黄嘌呤氧化酶可用于生成超氧自由基，测定超氧化物歧化酶的活性。
Features and Benefits
- 用于测定痕量金属含量（详情参见性质栏和技术规格说明书）
- 用于测定硫酸盐含量（详情参见性质栏和技术规格说明书）
General description
黄嘌呤及其衍生物天然存在于动物器官、酵母、土豆、咖啡豆和茶叶中。
黄嘌呤是一种嘌呤，可经由嘌呤代谢途径通过不同前体生成：
- 鸟嘌呤脱氨酶催化的鸟嘌呤脱氨
- 黄嘌呤氧化还原酶催化的次黄嘌呤转化
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1, 4-dicaffeoylquinic acid
Cao W, et al.
Journal of Molecular Structure, 1219, 128475-128475 null
Optimization of total phenolic contents, antioxidant, and in-vitro xanthine oxidase inhibitory activity of sunflower head
Mehmood A, et al.
CYTA-journal of Food, 16, 957-964 null
Resistance of postharvest biocontrol yeasts to oxidative stress: a possible new mechanism of action.
Raffaello Castoria et al.
Phytopathology, 93(5), 564-572 (2008-10-24)
ABSTRACT We detected the generation of the reactive oxygen species (ROS) superoxide anion ( O.(-) (2)) and hydrogen peroxide (H(2)O(2)) in apple wounds 2 immediately after wounding, and assessed the relationships between (i) timely colonization of apple wounds by biocontrol
Gavin C Higgins et al.
Free radical biology & medicine, 53(10), 1960-1967 (2012-09-18)
Neurons can undergo a diverse range of death responses under oxidative stress, encompassing apoptosis (caspase-dependent, programmed cell death) to various forms of caspase-independent death, including necrosis. We recently showed that primary murine cortical neurons exposed acutely to hydrogen peroxide undergo
Avery G Frey et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8031-8036 (2014-05-21)
Although cells express hundreds of metalloenzymes, the mechanisms by which apoenzymes receive their metal cofactors are largely unknown. Poly(rC)-binding proteins PCBP1 and PCBP2 are multifunctional adaptor proteins that bind iron and deliver it to ferritin for storage or to prolyl
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