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Merck
CN
所有图片(2)

文件

安全信息

WH0054206M1

Sigma-Aldrich

抗-ERRFI1单克隆抗体 小鼠抗

clone 2B9, purified immunoglobulin, buffered aqueous solution

别名:

抗-ERBB受体反馈抑制因子1, 抗-GENE33, 抗-MIG6, 抗-RALT

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

2B9, monoclonal

形式

buffered aqueous solution

种属反应性

human

技术

indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgG1κ

GenBank登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ERRFI1(54206)

一般描述

ERRFI1是一种细胞质蛋白,表达随细胞生长而上调(Wick et al., 1995 [PubMed 7641805])。它与大鼠基因-33的蛋白产物具有显著同源性,经细胞应激诱导产生并介导细胞信号传导(Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669])。[来源:OMIM]

免疫原

ERRFI1 (NP_061821, 111 a.a.~ 220 a.a)带有GST标签的部分重组蛋白。仅GST标签的分子量为26 KDa。

序列
VVCGFKKLTVNGVCASTPPLTPIKNSPSLFPCAPLCERGSRPLPPLPISEALSLDDTDCEVEFLTSSDTDFLLEDSTLSDFKYDVPGRRSFRGCGQINYAYFDTPAVSAA

外形

溶于pH7.4的磷酸盐缓冲盐水中的溶液

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。

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WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Liying Xing et al.
Journal of cell communication and signaling (2022-10-26)
Although mitogen-inducible gene 6 (MIG6) is highly expressed in vascular endothelial cells, it remains unknown whether MIG6 affects vascular permeability. Here, we show for the first time a critical role of MIG6 in limiting vascular permeability. We unveil that genetic
Lixian Liu et al.
Frontiers in cell and developmental biology, 9, 634242-634242 (2021-03-12)
The mitogen-inducible gene 6 (MIG6) is an adaptor protein widely expressed in vascular endothelial cells. However, it remains unknown thus far whether it plays a role in angiogenesis. Here, using comprehensive in vitro and in vivo model systems, we unveil
Myriam Lemmens et al.
Molecular therapy. Methods & clinical development, 23, 241-253 (2021-10-28)
Off-target editing is one of the main safety concerns for the use of CRISPR-Cas9 genome editing in gene therapy. These unwanted modifications could lead to malignant transformation, which renders tumorigenicity assessment of gene therapy products indispensable. In this study, we
Steven M Hill et al.
Cell systems, 4(1), 73-83 (2016-12-27)
Signaling networks downstream of receptor tyrosine kinases are among the most extensively studied biological networks, but new approaches are needed to elucidate causal relationships between network components and understand how such relationships are influenced by biological context and disease. Here, we investigate

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