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生化/生理作用
蟛蜞菊内酯通过阻断 IκBα 的磷酸化和降解抑制细胞内的 NF-κB- 介导的基因转录。IKKα 和 β激酶活性不可逆抑制剂（IC 50 <10βM）。蟛蜞菊内酯对 p38 MAP 激酶或 Akt 没有影响。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 1
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
R K Roy et al.
Archives of dermatological research, 300(7), 357-364 (2008-05-15)
Alopecia is a dermatological disorder with psychosocial implications on patients with hair loss. Eclipta alba Hassk. is a well-known Ayurvedic herb with purported claims of hair growth promotion. In the reported work attempts were undertaken to evaluate petroleum ether and
Luciana C Diogo et al.
Basic & clinical pharmacology & toxicology, 104(4), 293-299 (2009-03-27)
We genetically modified Eclipta alba using Agrobacterium rhizogenes LBA 9402, with the aim of producing secondary metabolites with pharmacological properties against phospholipase A(2) and the myotoxic activities of snake venom. Extracts from in natura aerial parts and roots, both native
Sivalokanathan Sarveswaran et al.
International journal of oncology, 41(6), 2191-2199 (2012-10-19)
Emerging studies indicate that metabolism of arachidonic acid through the 5-lipoxygenase (5-Lox) pathway plays a critical role in the survival of prostate cancer cells raising the possibility that 5-Lox can be targeted for an effective therapy of prostate cancer. Wedelolactone
Wei Zhang et al.
Toxicology letters, 209(2), 107-112 (2011-12-31)
The endothelin B2 (ET(B2)) receptors are induced in vascular smooth muscle cells (VSMCs) in cardiovascular diseases. We tested if in vitro short-term exposure to the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α) could up-regulate ET(B2) receptors in rat mesenteric arteries, and
Seyoung Lim et al.
Journal of cellular biochemistry, 113(11), 3436-3445 (2012-06-09)
Wedelolactone is an herbal medicine that is used to treat septic shock, hepatitis and venom poisoning. Although in differentiated and cancer cells, wedelolactone has been identified as anti-inflammatory, growth inhibitory, and pro-apoptotic, the effects of wedelolactone on stem cell differentiation
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