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Merck
CN

V4015

Sigma-Aldrich

毛蕊花苷

≥99% (HPLC)

别名:

类叶升麻苷, 麦角甾苷

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About This Item

经验公式(希尔记法):
C29H36O15
CAS号:
分子量:
624.59
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

≥99% (HPLC)

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

room temp

SMILES字符串

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

InChI key

FBSKJMQYURKNSU-ZLSOWSIRSA-N

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一般描述

毛蕊花苷,又称 毛蕊花糖苷,是一种亲水性植物化合物,首次从毛蕊花属植物中分离出来(Verbascum sinuatum L.)。毛蕊糖苷的化学结构包括羟基苯基乙基和肉桂酸部分,通过糖苷键与β-吡喃葡萄糖结合。

应用

毛蕊花苷已被:
  • 用作高效液相色谱分析(HPLC)的参考标准品
  • 用作参考标准品,通过高效液相色谱(HPLC)-二极管阵列检测器(DAD)-qTOF系统,对橄榄厂废水和废渣中酚类化合物进行检测
  • 在HEP2细胞和A549细胞中检测对呼吸道合胞病毒(RSV)的抗病毒活性

生化/生理作用

毛蕊花苷具有抗炎和光保护特性。它对PC12神经细胞具有神经毒性保护作用。在体外研究中,毛蕊花糖苷被证明是黄嘌呤氧化酶(XOD)的有效抑制剂。
苯乙醇苷。抗氧化和抗增殖。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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Guo-Qing Sheng et al.
European journal of pharmacology, 451(2), 119-124 (2002-09-17)
The neuroprotective effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 neuronal cells were investigated. Treatment of PC12 cells with MPP(+) for
Kiramage Chathuranga et al.
Viruses, 11(7) (2019-07-07)
The herbs Plantago asiatica and Clerodendrum trichotomum have been commonly used for centuries in indigenous and folk medicine in tropical and subtropical regions of the world. In this study, we show that extracts from these herbs have antiviral effects against
Augusto G Filho et al.
Phytotherapy research : PTR, 26(10), 1472-1475 (2012-01-26)
The phenylpropanoid glycoside verbascoside [2-(3,4-dihydroxyphenylethyl)-1-O-α-L-rhamnopyranosyl-(1→3)-β-D-(4-O-caffeyl)-glucopyranoside] (1) has been isolated as the main constituent of the crude extract of Buddleja brasiliensis Jacq. ex Spreng from Southern Brazil. The crude extract, main fractions and the compound 1 were evaluated for inhibition of
Hong-Quan Wang et al.
Neurotoxicity research, 21(4), 368-378 (2011-12-08)
Our previous study has shown that acteoside, an antioxidative phenylethanoid glycoside, protect against beta-amyloid (Aβ)-induced cytotoxicity in vitro. However, the precise protective mechanisms remains unclear. Heme oxygenase-1 (HO-1) is a crucial factor in the response to oxidative injury, protecting neurons
Luis Felipe Santos-Cruz et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(3-4), 1082-1090 (2011-12-27)
Verbascoside (VB) is a phenylpropanoid isolated from Buddleja species, some of which originate in Mexico, and was first described in the sixteenth century in the codices of Mexican traditional medicine. VB is present in alcohol extracts and is widely used

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