V3501
维生素 K 1
viscous liquid
别名:
2-甲基-3-植基-1,4-萘醌, 叶绿醌, 植物甲萘醌, 维生素 K1(20)
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关于此项目
经验公式（希尔记法）:
C31H46O2
化学文摘社编号:
分子量:
450.70
NACRES:
NA.28
PubChem Substance ID:
eCl@ss:
34058015
UNSPSC Code:
12352205
EC Number:
201-564-2
MDL number:
Beilstein/REAXYS Number:
2568816
产品名称
维生素 K 1, viscous liquid
InChI
1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
InChI key
MBWXNTAXLNYFJB-NKFFZRIASA-N
SMILES string
O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
biological source
synthetic (organic
inorganic)
form
viscous liquid
color
, Yellow to Very Dark Yellow to Very Dark Orange
refractive index
n20/D 1.527 (lit.)
mp
−20 °C (lit.)
density
0.984 g/mL at 25 °C (lit.)
storage temp.
2-8°C
Quality Level
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Application
维生素K1 用于制备培养基。
Biochem/physiol Actions
维生素K1（叶绿醌）是脂溶性多环芳香酮，用作辅因子，形成凝血因子II（凝血酶原）、VII、IX和X以及抗凝血因子蛋白C和抗凝血因子蛋白S，也可用作细胞信号传导因子。维生素K1对凝血、骨骼和血管代谢至关重要。人类膳食中维生素K 最重要的来源是绿叶蔬菜和植物油中所含的叶绿醌。
General description
维生素K1/叶绿醌是异戊烯化的萘醌。由植物、绿藻和某些种类的蓝细菌产生。
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Phylloquinone (vitamin K1): occurrence, biosynthesis and functions
Basset J G, et al.
Mini-Reviews in Medicinal Chemistry (2017)
Bacteroides disiens sp. nov. and Bacteroides bivius sp. nov. from human clinical infections
Holdeman L V and Johnson J L
International Journal of Systematic and Evolutionary Microbiology (1977)
Beverly Murray et al.
The Journal of antimicrobial chemotherapy, 75(8), 2149-2155 (2020-04-15)
Ibezapolstat (ACX-362E) is the first DNA polymerase IIIC inhibitor undergoing clinical development for the oral treatment of Clostridioides difficile infection (CDI). In this study, the in vitro activity of ibezapolstat was evaluated against a panel of 104 isolates of C.
Edward P A Gebuis et al.
Haematologica, 96(4), 583-589 (2011-01-05)
Poor anticoagulant stability in patients using vitamin K antagonists is a risk factor for both bleeding and thrombosis. In previous studies supplementation with low dose vitamin K(1) was shown to improve the stability of anticoagulant control. We set up a
Ellen M Apalset et al.
Bone, 49(5), 990-995 (2011-08-16)
Evidence of the effect of vitamin K on bone health is conflicting. The aim was to investigate the association between intake of vitamins K1 and K2 and subsequent risk of hip fracture in a general population sample, as well as
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