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Merck
CN
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文件

UC448

Sigma-Aldrich

硫酸对乙酰氨基酚钾盐 钾盐

solid, ≥97% (HPLC)

别名:

4-乙酰氨基苯酚硫酸酯 钾盐, N-（4-亚砜基苯基）乙酰胺 单钾盐, 硫酸对乙酰氨基酚 钾盐

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About This Item

经验公式（希尔记法）:
C8H8KNO5S
CAS号:
32113-41-0
分子量:
269.32
MDL编号:
MFCD01631667
UNSPSC代码:
12161501
PubChem化学物质编号:
329827671
NACRES:
NA.77

质量水平

200

检测方案

≥97% (HPLC)

形式

solid

颜色

white to off-white

mp

163 °C

溶解性

H2O: soluble

储存温度

2-8°C

SMILES字符串

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1

InChI key

AJYPYWFCUWHZMZ-UHFFFAOYSA-M

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一般描述

对乙酰氨基酚是一种氨基酚衍生物。具有镇痛解热作用，致炎作用弱。对乙酰氨基酚用于治疗发热和轻度至中度疼痛。它可能通过抗氧化作用抑制动脉粥样硬化。

应用

硫酸对乙酰氨基酚钾盐已用作对乙酰氨基酚 HPLC 含量测定的标准品 。

生化/生理作用

对乙酰氨基酚的 II 相代谢产物。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

制备说明

硫酸对乙酰氨基酚钾盐溶于水。

其他说明

偶尔，可能需要以钠盐形式供应

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Hayati Filik et al.
Chemical & pharmaceutical bulletin, 54(6), 891-896 (2006-06-07)
In the present paper, conventional spectrophotometry in conjunction with cloud point extraction-preconcentration were investigated as alternative methods for paracetamol (PCT) assay in urine samples. Cloud point extraction (CPE) was employed for the preconcentration of p-aminophenol (PAP) prior to spectrophotometric determination
D Bougie et al.
Blood, 97(12), 3846-3850 (2001-06-05)
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in
Karel Allegaert et al.
Acta paediatrica (Oslo, Norway : 1992), 94(9), 1273-1279 (2005-11-11)
Major changes in drug clearance and metabolism are observed during infancy, in part based on ontogenic regulation of various metabolic pathways. Since paracetamol provides a good substrate to study UGT (1A6) activity, urinary metabolites of propacetamol were determined in neonates
Paracetamol: past, present, and future.
Prescott LF
American Journal of Therapeutics, 7(2), 143-147 (2000)
A K Hewavitharana et al.
Analytical biochemistry, 374(1), 106-111 (2007-12-18)
An HPLC-MS/MS method has been developed for the selective quantitative analysis of paracetamol and its two major metabolites. The use of tandem MS enabled the detection and quantitation of metabolites in small sample sizes with high sensitivity and selectivity. Isocratic
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