UC448
硫酸对乙酰氨基酚钾盐 钾盐
≥97% (HPLC), analgesic agent, solid
别名:
4-乙酰氨基苯酚硫酸酯 钾盐, N-（4-亚砜基苯基）乙酰胺 单钾盐, 硫酸对乙酰氨基酚 钾盐
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关于此项目
经验公式（希尔记法）:
C8H8KNO5S
化学文摘社编号:
分子量:
269.32
UNSPSC Code:
12161501
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
硫酸对乙酰氨基酚钾盐 钾盐, solid, ≥97% (HPLC)
SMILES string
[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1
InChI
1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1
InChI key
AJYPYWFCUWHZMZ-UHFFFAOYSA-M
assay
≥97% (HPLC)
form
solid
color
white to off-white
mp
163 °C
solubility
H2O: soluble
storage temp.
2-8°C
Quality Level
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Application
硫酸对乙酰氨基酚钾盐已用作对乙酰氨基酚 HPLC 含量测定的标准品 。
Biochem/physiol Actions
对乙酰氨基酚的 II 相代谢产物。
General description
对乙酰氨基酚是一种氨基酚衍生物。具有镇痛解热作用，致炎作用弱。对乙酰氨基酚用于治疗发热和轻度至中度疼痛。它可能通过抗氧化作用抑制动脉粥样硬化。
Other Notes
偶尔，可能需要以钠盐形式供应
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
Preparation Note
硫酸对乙酰氨基酚钾盐溶于水。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Karel Allegaert et al.
Acta paediatrica (Oslo, Norway : 1992), 94(9), 1273-1279 (2005-11-11)
Major changes in drug clearance and metabolism are observed during infancy, in part based on ontogenic regulation of various metabolic pathways. Since paracetamol provides a good substrate to study UGT (1A6) activity, urinary metabolites of propacetamol were determined in neonates
Paracetamol: past, present, and future.
Prescott LF
American Journal of Therapeutics, 7(2), 143-147 (2000)
D Bougie et al.
Blood, 97(12), 3846-3850 (2001-06-05)
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in
Caroline D van der Marel et al.
European journal of clinical pharmacology, 59(3), 243-251 (2003-05-23)
Data concerning metabolism of paracetamol in infants are scant. Previous studies have examined urinary metabolite recovery rates after a single dose of paracetamol in either neonates (<6 weeks) or children (3-9 years). There are no studies investigating infants. Infants (
A Alberti et al.
Biological psychiatry, 46(3), 420-424 (1999-08-06)
Parents of autistic children and autism support groups often report that autistic episodes are exacerbated when the children eat certain foodstuffs such as dairy products, chocolates, wheat, corn sugar, apples, and bananas. The hypothesis that autistic behavior might be related
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