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应用
O-Desmethylnaproxen can be used for assaying naproxen metabolites.
生化/生理作用
CYP2C9 metabolite of naproxen
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Da-Fang Zhong et al.
Acta pharmacologica Sinica, 24(5), 442-447 (2003-05-13)
The metabolites of naproxen produced by Cunninghamella species were isolated and identified, and further to compare the similarities between microbial transformation and mammalian metabolism. Naproxen was transformed by three strains of Cunninghammella species (Cunninghamella blakeslesna AS 3.153, Cunninghamella echinulata AS
P L Walker et al.
Annals of clinical biochemistry, 24 ( Pt 2), 177-181 (1987-03-01)
Interference by naproxen in the spectrophotometric assay for urinary 5-hydroxyindoleacetic acid has been investigated. Gas chromatography-mass spectrometry demonstrated that ingestion of naproxen was associated with the production of four urinary components, unchanged drug and three metabolites, the major one being
J L Shimek et al.
Journal of pharmaceutical sciences, 71(4), 436-439 (1982-04-01)
An isocratic high-pressure liquid chromatographic method for the determination of naproxen and its desmethyl metabolite in human plasma is presented. A reversed-phase octadecylsilane column was utilized with a mobile phase consisting of 55% methanol and 45% 0.10 M acetate buffer
Kushari Bowalgaha et al.
British journal of clinical pharmacology, 60(4), 423-433 (2005-09-29)
To characterize the kinetics of S-naproxen ('naproxen') acyl glucuronidation and desmethylnaproxen acyl and phenolic glucuronidation by human liver microsomes and identify the human UGT isoform(s) catalysing these reactions. Naproxen and desmethylnaproxen glucuronidation were investigated using microsomes from six and five
Stephanie Selke et al.
Journal of chromatography. A, 1217(3), 419-423 (2009-12-17)
O-desmethylnaproxen (2-(6-hydroxynaphthalen-2-yl)propanoic acid) was identified in 10 different water samples from Germany and Pakistan. In the Pakistan samples it was found in all samples, surface water and effluents, exhibiting estimated concentrations between 0.04 and 1.36 microg/L. In Germany it was
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