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应用
O-Desmethylnaproxen can be used for assaying naproxen metabolites.
生化/生理作用
CYP2C9 metabolite of naproxen
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
T B Vree et al.
Biopharmaceutics & drug disposition, 14(6), 491-502 (1993-08-01)
The aim of this investigation was to assess the pharmacokinetics of naproxen in 10 human subjects after an oral dose of 500 mg using a direct HPLC analysis of the acyl glucuronide conjugates of naproxen and its metabolite O-desmethylnaproxen. The
H Yokoyama et al.
Human & experimental toxicology, 13(12), 831-838 (1994-12-01)
1. Rat liver microsomal suspension containing NADPH and MgCl2 was incubated at 37 degrees C with naproxen, a non-steroidal anti-inflammatory drug. Thiobarbituric acid reactive substances (TBA-RS), high molecular weight protein aggregates and fluorescent substances were formed in the microsomal suspension.
C H Kiang et al.
Drug metabolism and disposition: the biological fate of chemicals, 17(1), 43-48 (1989-01-01)
A new metabolite of naproxen, 6-desmethylnaproxen sulfate (6-DMNS), has been identified in plasma from normal and uremic subjects after oral administration of a single 500 mg dose of naproxen. Tentative identification was achieved by the finding of an increase in
Da-Fang Zhong et al.
Acta pharmacologica Sinica, 24(5), 442-447 (2003-05-13)
The metabolites of naproxen produced by Cunninghamella species were isolated and identified, and further to compare the similarities between microbial transformation and mammalian metabolism. Naproxen was transformed by three strains of Cunninghammella species (Cunninghamella blakeslesna AS 3.153, Cunninghamella echinulata AS
P L Walker et al.
Annals of clinical biochemistry, 24 ( Pt 2), 177-181 (1987-03-01)
Interference by naproxen in the spectrophotometric assay for urinary 5-hydroxyindoleacetic acid has been investigated. Gas chromatography-mass spectrometry demonstrated that ingestion of naproxen was associated with the production of four urinary components, unchanged drug and three metabolites, the major one being
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