生物来源
synthetic (organic)
质量水平
产品线
BioUltra
检测方案
≥99%
形式
powder
杂质
≤0.016% Phosphorus (P)
≤0.1% Insoluble matter
灼烧残渣
≤0.2%
mp
163-167 °C (lit.)
溶解性
H2O: 0.1 M, clear, colorless
痕量阳离子
Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.005%
Mg: ≤0.003%
NH4+: ≤0.15%
Na: ≤0.02%
Pb: ≤0.005%
Zn: ≤0.0005%
SMILES字符串
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI key
DRTQHJPVMGBUCF-XVFCMESISA-N
基因信息
mouse ... Uck1(22245)
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一般描述
尿苷是一种嘧啶核苷,对 RNA 和膜的合成至关重要。它通过形成嘧啶核苷酸-脂质缀合物来帮助正常细胞功能和生长。
应用
尿苷已被用于研究原生动物寄生虫的核苷水解酶和哺乳动物尿苷磷酸化酶在酿酒酵母的URH1(尿苷水解酶)上的功能互补。
它已用于检查长期应用尿苷对小鼠肝脏代谢的影响。
它已用于检查长期应用尿苷对小鼠肝脏代谢的影响。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice.
PLoS ONE, 11, e0146994-e0146994 (2016)
Purinergic and Pyrimidinergic Signalling: Molecular, Nervous and Urogenitary System Function
Handbook of Experimental Pharmacology (2013)
Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase.
Applied and Environmental Microbiology, 68, 1336-1343 (2002)
Nature methods, 17(10), 991-1001 (2020-09-02)
Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-seq), a method for massively parallel analysis of newly transcribed and pre-existing mRNAs from the same
Journal of medicinal chemistry, 56(6), 2348-2358 (2013-02-16)
Resistance by Plasmodium falciparum to almost all clinically used antimalarial drugs requires the development of new classes of antimalarials. 6-Iodouridine (15), a novel and potent inhibitor of orotidine 5'-monophosphate decarboxylase (ODCase), exhibited efficacy in a mouse model infected by P.
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