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Merck
CN

U5252

尿苷 5′-二磷酸-N-乙酰半乳糖胺 二钠盐

≥97%, synthetic (organic), powder

别名:

UDP-N-乙酰半乳糖胺, 尿苷[5′]二磷酸[1]（2-乙酰氨基-2-脱氧 - α-D吡喃半乳糖） 二钠盐, 尿苷二磷酸半乳糖

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关于此项目

经验公式（希尔记法）:
C17H25N3Na2O17P2
化学文摘社编号:
108320-87-2
分子量:
651.32
NACRES:
NA.51
PubChem Substance ID:
24900653
UNSPSC Code:
41106305
MDL number:
MFCD00077894
Beilstein/REAXYS Number:
5375867
Assay:
≥97%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
−20°C

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产品名称

尿苷 5′-二磷酸-N-乙酰半乳糖胺 二钠盐, ≥97%

InChI key

HXWKMJZFIJNGES-QCVFHWOISA-L

SMILES string

[Na+].[Na+].CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O

InChI

1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11+,12-,13-,14-,15?,16?;;/m1../s1

biological source

synthetic (organic)

assay

≥97%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

200

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相关类别

Application

尿苷5′-二磷酸-N-乙酰半乳糖胺二钠盐已用作多肽N-乙酰半乳糖胺转移酶(ppGalNAc-T)的底物。

General description

尿苷二磷酸(UDP)-GalNAc用作O-连接寡糖生物合成的前体。它还可作为甲壳素合成底物，甲壳素是真菌细胞壁以及节肢动物和昆虫外骨骼的主要成分。

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000526683
0000526677
0000526683
0000526677
0000492016

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Expression of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase isozymes T1 and T2 in human colorectal cancer
Kohsaki T, et al.
Journal of Gastroenterology, 35(11), 840-848 (2000)
Daniel R Evans et al.
Human mutation, 39(8), 1092-1101 (2018-05-12)
Characterizing moderate penetrance susceptibility genes is an emerging frontier in colorectal cancer (CRC) research. GALNT12 is a strong candidate CRC-susceptibility gene given previous linkage and association studies, and inactivating somatic and germline alleles in CRC patients. Previously, we found rare
Hongwei Wu et al.
Nucleic acids research, 33(9), 2822-2837 (2005-05-20)
We present a computational method for the prediction of functional modules encoded in microbial genomes. In this work, we have also developed a formal measure to quantify the degree of consistency between the predicted and the known modules, and have
Anthony P Corfield
Microorganisms, 6(3) (2018-08-04)
Glycoproteins are major players in the mucus protective barrier in the gastrointestinal and other mucosal surfaces. In particular the mucus glycoproteins, or mucins, are responsible for the protective gel barrier. They are characterized by their high carbohydrate content, present in
Earnest James Paul Daniel et al.
Glycobiology, 30(11), 910-922 (2020-04-19)
A family of polypeptide GalNAc-transferases (GalNAc-Ts) initiates mucin-type O-glycosylation, transferring GalNAc onto hydroxyl groups of Ser and Thr residues of target substrates. The 20 GalNAc-T isoenzymes in humans are classified into nine subfamilies according to sequence similarity. GalNAc-Ts select their
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