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Merck
CN

U4883

Supelco

尿素

8 M (after reconstitution with 16 mL high purity water)

别名:

尿素 溶液, 碳酰二胺, 碳酰胺

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About This Item

线性分子式:
NH2CONH2
CAS号:
分子量:
60.06
Beilstein:
635724
EC 号:
MDL编号:
UNSPSC代码:
12352111
PubChem化学物质编号:
NACRES:
NA.25

形式

powder

质量水平

浓度

8 M (after reconstitution with 16 mL high purity water)

溶解性

H2O: soluble (1 vial plus 16 mL)

SMILES字符串

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

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一般描述

尿素是一种离液剂,适用于蛋白质变性。它能够破坏蛋白质二级、三级和四级结构中的氢键。它还可以破坏DNA二级结构中的氢键。

应用

适用于在准备2D-PAGE、酶解消化物、IMAC色谱以及相关操作流程中使蛋白质溶解和变性。
尿素已可用于反相纳米喷雾液相色谱-串联质谱法中的蛋白质样品制备。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Sheehan D
Physical Biochemistry: Principles and Applications (2009)
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals.
Jin L, et al.
Molecular and Cellular Biology, 28, 5014-5026 (2008)
L Li et al.
Cell death and differentiation, 22(7), 1081-1093 (2014-12-20)
P53 is critically important in preventing oncogenesis but its role in inflammation in general and in the function of inflammatory macrophages in particular is not clear. Here, we show that bone marrow-derived macrophages exhibit endogenous p53 activity, which is increased
A mechanically and electrically self-healing supercapacitor.
Hua Wang et al.
Advanced materials (Deerfield Beach, Fla.), 26(22), 3638-3643 (2014-02-21)
Sreenivasa C Ramaiahgari et al.
Archives of toxicology, 88(5), 1083-1095 (2014-03-07)
Immortalized hepatocyte cell lines show only a weak resemblance to primary hepatocytes in terms of gene expression and function, limiting their value in predicting drug-induced liver injury (DILI). Furthermore, primary hepatocytes cultured on two-dimensional tissue culture plastic surfaces rapidly dedifferentiate

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