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安全信息

U4500

Sigma-Aldrich

尿苷5′-二磷酸半乳糖 二钠盐

≥97.0%

别名:

UDP-Gal, UDP-半乳糖

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5 G
¥1,411.82
25 G
¥6,576.16
100 G
¥10,723.17

¥1,411.82

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5 G
¥1,411.82
25 G
¥6,576.16
100 G
¥10,723.17

About This Item

经验公式（希尔记法）:
C15H22N2Na2O17P2
CAS号:
137868-52-1
分子量:
610.27
MDL编号:
MFCD00077895
UNSPSC代码:
41106305
PubChem化学物质编号:
24900647
NACRES:
NA.51

¥1,411.82

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生物来源

bovine milk
rabbit muscle
yeast

质量水平

200

方案

≥97.0%

表单

powder

储存温度

−20°C

SMILES字符串

[Na+].[Na+].OC[C@H]1O[C@@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8+,9-,10+,11-,12-,13?,14?;;/m1../s1

InChI key

PKJQEQVCYGYYMM-OUJOOSCPSA-L

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此商品
D6001D8906D6924
Dextran sulfate sodium salt from Leuconostoc spp. low sulfate content, Mr ~40,000

52423

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

D6001

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. Molecular Biology, average Mw >500,000 (dextran starting material), contains 0.5-2% phosphate buffer

D8906

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. average mol wt 9,000-20,000

D6924

Dextran sulfate sodium salt from Leuconostoc spp.

biological source

(Leuconostoc spp)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

synthetic

biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

room temp

useful pH range

6.0-8 (10 g/L)

useful pH range

6.0-8.0 (1% in water)

useful pH range

6.0-8 (10 g/L)

useful pH range

5.5 - 8.0

一般描述

尿苷5′-二磷酸-α-D-半乳糖/UDP-Gal是一种核苷酸糖。[1]

应用

尿苷5′二磷酸半乳糖二钠盐已用作半乳糖基转移酶标记缓冲液组分，用于预先标记免疫球蛋白链末端的N-乙酰葡萄糖胺(GlcNAc)。[2]它还用作羟脯氨酸O-半乳糖基转移酶(HPGT)检测组分。[3]

生化/生理作用

尿苷5′-二磷酸-α-D-半乳糖/UDP-Gal可抑制BALB/3T12细胞发育。[4]在哺乳动物中，它对于糖缀合物的生物合成至关重要。[1]

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000407572
    0000377363
    0000341179
    0000341180
    0000331698

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    Enzymatic synthesis of UDP-galactose on a gram scale
    Bulter T and Elling L
    Journal of Molecular Catalysis. B, Enzymatic, 8(4-6), 281-284 (2000)
    LC/MS-based Detection of Hydroxyproline O-galactosyltransferase Activity
    Ogawa-Ohnishi M and Matsubayashi Y
    Bio-protocol, 19(10), 4130-4140 (2016)
    UDP-galactose inhibition of BALB/3T12-3 cell growth: Requirement for medium galactosyltransferase activity
    Klohs W D, et al.
    Experimental Cell Research, 141(2), 365-374 (1982)
    Susannah M L Gagnon et al.
    The Journal of biological chemistry, 290(45), 27040-27052 (2015-09-17)
    Homologous glycosyltransferases α-(1→3)-N-acetylgalactosaminyltransferase (GTA) and α-(1→3)-galactosyltransferase (GTB) catalyze the final step in ABO(H) blood group A and B antigen synthesis through sugar transfer from activated donor to the H antigen acceptor. These enzymes have a GT-A fold type with characteristic
    Robyn Meech et al.
    Molecular pharmacology, 87(3), 442-450 (2014-12-19)
    The human UDP glycosyltransferase (UGT) superfamily comprises four families of enzymes that catalyze the addition of sugar residues to small lipophilic chemicals. The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conjugate
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