DMT-2′Fluoro-dU Phosphoramidite

生物来源

non-animal source (no BSE/TSE risk)

质量水平

300

产品线

Proligo Reagents

检测方案

≥99% (³¹P-NMR)
≥99.0% (reversed phase HPLC)

形式

powder

技术

oligo synthesis: suitable

杂质

≤0.3% water content (Karl Fischer)
≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR)
≤0.5% single Impurity (reversed phase HPLC)
≤3% residual Solvent content

颜色

white to off-white

λ

conforms (UV/VIS Identity)

适用性

conforms to structure for H-NMR
conforms to structure for LC-MS

相容性

configured for PerkinElmer
configured for Polygen

核苷分析

base: deoxyuridine
base protecting group: none
2' protecting group: fluoro
5' protecting group: DMT
deprotection: fast/standard

储存温度

−20°C

SMILES字符串

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](F)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5

InChI

1S/C39H46FN4O8P/c1-26(2)44(27(3)4)53(50-24-10-22-41)52-36-33(51-37(35(36)40)43-23-21-34(45)42-38(43)46)25-49-39(28-11-8-7-9-12-28,29-13-17-31(47-5)18-14-29)30-15-19-32(48-6)20-16-30/h7-9,11-21,23,26-27,33,35-37H,10,24-25H2,1-6H3,(H,42,45,46)/t33-,35-,36-,37-,53?/m1/s1

InChI key

HQHQPAYRJJMYQX-DJTPZYMWSA-N